Diabetic foot microbiology (original) (raw)
Related papers
2009
Objective: To determine frequency and extent of foot lesion and the susceptibility pattern of infective organisms in Diabetic foot. Design: (Descriptive) cross sectional study Place and duration of study: Surgical Unit –II Holy Family Hospital, Rawalpindi completed in 4 months (5 Feb.2008 to 5 June, 2008) Patients and methods: A total of 50 consecutive patients with diabetic foot lesions were assessed for angiopathy, neuropathy and extent of foot lesion. Necessary investigations including x-ray foot, pus for culture & sensitivity and fungal scraping were carried out. Results: 40% of total patients were insulin dependent diabetics (IDDM) out of which 80% were on irregular treatment. 52% of total patients were non insulin dependent (NIDDM) out of which 73% were on irregular treatment and 8% of total patients were getting no treatment. Most of the infection were due to staphylococcus aureus (22%), pseudomonas (18%) Proteus (16%) E.Coli (12%) Streptococci(12%). Angiopathy was present in...
Clinical, Pathological and Microbiological Evaluation of Diabetic Foot Syndrome
Medicina, 2020
Background and objectives: Diabetic foot ulcer (DFU) is one of the serious complications of diabetes, being related to frequent and long-term hospitalisation, reduced quality of life of the patient, amputations, a high rate of morbidity and mortality. The bacterial aetiology is complex, sometimes involving more than one pathogen, playing a major role in the infection prognosis and development of microbial resistance. This study evaluated the current state of the aetiology, clinical and pathological characteristics of DFU in a single diabetes centre in order to provide some specific measures to prevent it. Materials and Methods: This retrospective study was conducted on patients with diabetes mellitus (252 individuals diagnosed with DFU) between January 2018–December 2019. All participants were assessed based on their clinical characteristics, including complications of diabetes and pathological and microbiological evaluations. Results: The present research revealed that diabetic foo...
Muller Journal of Medical Sciences and Research, 2013
To evaluate the clinical and microbiological profile of diabetic foot ulcer patients admitted to a tertiary care hospital. Methodology: This study recruited 120 diabetic foot ulcer patients of all grade. Their medical records were evaluated retrospectively. Results: We found that median age of patient was 60(52, 67.75) years. 68.3% of patients were males. Median duration of diabetes mellitus was 15(10, 20) years. Mean HbA1C and fasting glucose was 10.3 AE 2.3 and 167.6 AE 52.42 respectively. Neuropathy (35%) and peripheral vascular disease (23.3%) was major micro vascular and macro vascular complication associated. Different locations of ulcers were toe (23.3%), sole (20%), dorsum (18.3%), shin (16.6%), heel (13.3%), and ankle (8.3%). Bacterial infection was seen in 81.66% patients out of which 23.3% had poly microbial infection. Conclusion: Diabetic foot ulcer patient had poor blood glucose control with elevated HbA1C and fasting blood glucose level. Neuropathy and peripheral vascular disease, hypertension were major complications. Staphylococcus aureus, Pseudomonas aeruginosa were common infecting bacteria.
An evidence-based approach to diabetic foot infections
The American Journal of Surgery, 2003
Foot infections are a major complication of diabetes mellitus and contribute to the development of gangrene and lower extremity amputation. Recent evidence indicates that persons with diabetes are at greater risk for infection because of underlying neuropathy, peripheral vascular disease, and impaired responses to infecting organisms. This article reviews the underlying pathophysiology, causes, microbiology, and current management concepts for this potentially limb-threatening complication. Multidisciplinary management consisting of teams of specialists with a focus on limb preservation can make significant improvements in outcomes, including a reduction in rates of lower extremity amputation.
Clinico-microbiological profile and outcome of diabetic foot ulcers
International Surgery Journal, 2020
Background: Diabetic foot ulcers (DFU) are debilitating to the patients and significantly impair their quality of life. DFU associated with infection have the worst outcomes and may lead to amputations if timely intervention is not done. In the present study, aim was to identify the association between the type of organism isolated and the rates of amputations in diabetic foot ulcers.Methods: We retrospectively studied 50 diabetic foot ulcers from January 2017 to June 2017, who were in-patients in a single unit of surgery department in King George Hospital, Visakhapatnam. Baseline clinical examination was done. Parameters such as age, sex, duration, diabetic status and its treatment, organisms isolated, various treatment options for ulcers and the outcomes were studies.Results: Males were the predominant study subjects (M: F=32:18). The age of presentation was 18-65 years with an average of 46 years. Gram negative organisms were the frequent microbial isolates, all being mono-microb...
Diabetic foot infections and their management in a tertiary care hospital
Journal of Ayub Medical College, Abbottabad : JAMC
Diabetic foot is a common complication of diabetes world over. We conducted this study to determine common microbiological pathogens in Diabetic Foot Infections (DFI) at a tertiary care hospital and their management. In this observational study deep wound swabs of all admitted diabetic patients were taken, pathogens isolated, antibiotic used and its response depending on complete resolution of symptoms and biochemical markers were recorded. Data were analysed on SPSS-11. A total of 114 cases were recorded. Sixty-eight (59%) cases had ulcers on forefoot, 28 (25%) mid-foot and 18 (16%) hind-foot. One hundred and four pathogens were isolated from wound swabs after debridement. Commonest pathogen isolated was Staphylococcus aureus (52, 46%) followed by E. coli (11, 10%), MRSA was found in 10 (9%) cases, streptococcus in 6 (5%) and pseudomonas in 5 (4%) cases. Polymicrobial infection was also seen in a few cases. Surgical intervention included superficial debridement in 88 (77%) cases, t...
A PROSPECTIVE STUDY OF DIABETIC FOOT INFECTIONS (DIFs) IN A TEACHING HOSPITAL OF SEMI URBAN SETUP
International journal of scientific research, 2016
Background: Diabetic foot ulcer (DFIs) as the leading cause of lower limb amputation is one of the most important complications of diabetes mellitus (DM). The Indian diabetic population is expected to increase to 57 million by the year 2025. Mostly, the diabetic foot infections are mixed bacterial infections and the proper management of these infections requires an appropriate antibiotic selection, based on the culture and the antimicrobial susceptibility testing results. Hence, an attempt was made with the aim of determining the bacterial profile of infected diabetic foot ulcers and their antimicrobial resistance pattern. Patients and Methods: One hundred and twenty six diabetic patients with foot ulcers were included in the present study during a period of one and half years. Aerobic bacterial isolation was done from the specimens of these patients and their antimicrobial sensitivity pattern was studied using standard bacteriological techniques. Results: A total of 178 bacterial isolates were obtained from 126 patients with diabetic foot infections. Gram negative bacilli were predominant (67.42%) than gram positive cocci. The commonest isolate was Escherichia coli (31.46%) followed by Staphyloccus aureus (17.98%). The DFIs were of polymicrobial in nature. Majority of the bacterial isolates were highly sensitive to Amikacin, Cefotaxime, Ceftriaxone, Gentamicin in both gram positive and negative group whereas Staphylococcus aureus including MRSA were sensitive to Vancomycin. Conclusions: DFIs are common in diabetics and pose serious health problems for developing countries. Long duration of hospitalization of patients with high percentage of the amputations and overall mortality rates highlight the high burden of DFIs and the significance of its prevention and early treatment. To conclude, a multidisciplinary approach can confer better treatment and outcome with respect to DFIs.
Diabetic Foot Infections and Outcomes: A Single Center Study
Infectious Diseases and Clinical Microbiology, 2021
Objective: Diabetic foot infections (DFI) is one of the most important complications of diabetes mellitus. In this study, we aimed to show the causative microorganisms among patients with DFI and evaluate the long term results. Materials and Methods: We included the patients over 18 years old who were followed up with DFI, with deep tissue cultures between July 26, 2015, and November 5, 2018, in our center. Demographic data of the patients, Hba1c levels, nasal swab, tissue biopsy and antibiogram results of microorganisms, were evaluated. The outcomes were infection, amputation, and mortality. Results: In total, 397 patients followed up with DFI diagnosis in "Diabetic Foot and Chronic Wound Unit" were included. The mean age was 65.48 years, and 74.3% of the patients were male. The most common gram-negative agent was Pseudomonas aeruginosa (37.1%), and the gram-positive agent was Staphylococcus aureus (56.5%). A surgical procedure was performed in 57.2% of the cases. Finger amputation interventions were 33.5% of the interventions, 36.6% were surgical debridement, and the remaining 30% were major amputations. The mortality rate was 1.5%. Conclusion: Tissue culturing is an important diagnostic tool that gives etiology and susceptibility pattern of bacteria in patients with DFI.