DNA Adduct Formation of 2-Amino-9H-pyrido[2,3-b]indole and 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline in Mouse Liver and Extrahepatic Tissues During a Subchronic Feeding Study
Yijin Tang
Toxicological Sciences, 2013
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Relative potency of fifteen pyrrolizidine alkaloids to induce DNA damage as measured by micronucleus induction in HepaRG human liver cells
Cathy Lester
Food and Chemical Toxicology, 2018
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Genotoxicity of pyrrolizidine alkaloids
Nan Mei
Journal of Applied Toxicology, 2010
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Pathological and immunohistochemical changes in the liver of monocrotaline-treated rats
Necati Timurkaan N
Turkish Journal of Veterinary & Animal Sciences, 2022
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Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid retrorsine in liver of F344 rats
Enas Jewaid
2011
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Hepatic DNA adduct formation in rats treated with benzo[f]quinoline
Chithan Kandaswami
Cancer Letters, 1988
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Excretion of DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine and 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline, PhIP- dG, PhIP-DNA and DiMeIQx-DNA from the rat
Henrik Frandsen
Carcinogenesis, 1997
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DNA Adduct Formation by 2,6-Dimethyl-, 3,5-Dimethyl-, and 3-Ethylaniline in Vivo in Mice
John Groopman
Chemical Research in Toxicology, 2006
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Metabolism and Elimination of the Endogenous DNA Adduct, 3-(2-Deoxy- -D-erythropentofuranosyl)-pyrimido[1,2- ]purine-10(3H)-one, in the Rat
Charles Knutson
Journal of Biological Chemistry, 2007
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DNA cross-linking in mammalian cells by pyrrolizidine alkaloids: Structure-activity relationships
Roger Coulombe
Toxicology and Applied Pharmacology, 1991
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Cytochrome P450-Mediated Metabolism and DNA Binding of 2-Amino-1,7-dimethylimidazo[4,5- g ]quinoxaline and Its Carcinogenic Isomer 2-Amino-3,8-dimethylimidazo[4,5- f ]quinoxaline in Mice
erin bessette
Chemical Research in Toxicology, 2012
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The potent hepatocarcinogen methapyrilene does not form DNA adducts in livers of Fischer 344 rats
G. Talaska
Mutation research, 1988
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Effects of suberoylanilide hydroxamic acid and trichostatin A on induction of cytochrome P450 enzymes and benzo[ a]pyrene DNA adduct formation in human cells
William Baird, Louisa Hooven
Bioorganic & Medicinal Chemistry Letters, 2005
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A comparison of the effects of 3'-methyl-4-dimethylaminoazobenzene, 2-methyl-4-dimethylaminoazobenzene, and 2-acetylaminofluorene on rat liver DNA stability and new synthesis
James Yager
Cancer research, 1975
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Formation of depurinating N3adenine and N7guanine adducts after reaction of 1,2-naphthoquinone or enzyme-activated 1,2-dihydroxynaphthalene with DNA
Muhammad Saeed
Chemico-Biological Interactions, 2007
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Formation of depurinating N3adenine and N7guanine adducts after reaction of 1,2-naphthoquinone or enzyme-activated 1,2-dihydroxynaphthalene with DNA. Implications for the mechanism of tumor initiation by naphthalene
Muhammad Saeed
Chemico Biological Interactions, 2007
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Identification and Quantitation of Dibenzo[a,l]pyrene-DNA Adducts Formed by Rat Liver Microsomes in Vitro: Preponderance of Depurinating Adducts
Ryszard Jankowiak
Biochemistry, 1995
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Syntheses of DNA-adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido(2,3-b)indole (MeAαC) and 2-amino- 9H-pyrido(2,3-b)indole (AαC) and identification of DNA-adducts in organs from rats dosed with MeAαC
Hanne Frederiksen
2010
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Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine
Richard Beger
Toxicology Letters, 2003
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DNA adduct formation by7H-dibenzo[c,g]carbazole and its tissue- and organ-specific derivatives in Chinese hamster V79 cell lines stably expressing cytochrome P450 enzymes
Radim Šrám
Environmental and Molecular Mutagenesis, 2004
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Comparison of cytochrome P450- and peroxidase-dependent metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in human cell lines: formation of stable DNA adducts and absence of a detectable increase in apurinic sites
Albrecht Seidel
Cancer research, 1999
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Mutations Induced by the Carcinogenic Pyrrolizidine Alkaloid Riddelliine in the Liver cII Gene of Transgenic Big Blue Rats
Nan Mei
Chemical Research in Toxicology, 2004
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The genotoxic potential of methapyrilene using the alkaline Comet assay in vitro and in vivo
Dominic Williams
Toxicology, 2011
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Oxidative DNA Damage Induced by Carcinogenic Dinitropyrenes in the Presence of P450 Reductase
KIYOSHI FUKUHARA
Chemical Research in Toxicology, 2004
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Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeA C) and 2-amino-9H-pyrido[2,3-b]indole (A C) and identification of DNA adducts in organs from rats dosed with MeA C
Henrik Frandsen, Hanne Frederiksen
Carcinogenesis, 2004
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DNA adduct level induced by 2-amino-3,4-dimethylimidazo[4,5- f ]-quinoline in Big Blue TM mice does not correlate with mutagenicity
Takayoshi Suzuki
Mutagenesis, 1998
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Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice
Minerva Ramos-gómez
Carcinogenesis, 2003
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Potentiation of CB 1954 cytotoxicity by reduced pyridine nucleotides in human tumour cells by stimulation of DT diaphorase activity
Patrick J Biggs
Biochemical Pharmacology, 1992
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Genotoxic and genoprotective effects of 1,4-dihydropyridine derivatives: a brief review
Evita Rostoka
Archives of Industrial Hygiene and Toxicology
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<emph type="2">In Vitro</emph> and <emph type="2">In Vivo</emph> Studies on Oxygen Free Radical and DNA Adduct Formation in Rat Lung and Liver during Benzo[a]pyrene Metabolism
Jacob Briedé
Free Radical Research, 2004
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