Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus-8) ORF54 Encodes a Functional DUTPase Expressed In the Lytic Replication Cycle (original) (raw)

Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus-8) ORF54 Encodes a Functional DUTPase Expressed In the Lytic Replication Cycle

Journal of General …, 1999

Abstract

The complete ORF54 of the Kaposi's sarcoma-associated herpesvirus (KSHV) (human herpes-virus-8; HHV-8) was cloned and expressed in E. coli. The results show that KSHV/HHV-8 ORF54 encodes a functional dUTPase which specifically hydrolyses dUTP ...

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