Iridoid and megastigmane glycosides from Phlomis aurea (original) (raw)

From the leaves of Phlomis aurea, two new iridoids of unique structures named 3-epiphlomurin (1) and phlomurin (2), a new megastigmane glucoside phlomuroside (3) and a new benzyl alcohol glycoside having the structure benzyl alcohol-O-b-xylopyranosyl-(132)-b-glucopyranoside (4) have been isolated together with four known iridoids auroside, lamiide, 8-epiloganin and ipolamiide, two known phenolic glycosides acteoside (verbascoside) and syringin, one known phenylethanoid glycoside 2-phenylethyl-O-b-xylopyranosyl-(132)-b-glucopyranoside, one known lignan liriodendrin and three known¯avonoids chrysoeriol-7-O-bglucopyranoside, acacetin-7-O-b-glucopyranoside and luteolin-7-O-b-glucopyranoside. The structures of the isolated compounds were veri®ed by means of mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectral analyses.