N152G, -S, and -T Substitutions in CMY-2  -Lactamase Increase Catalytic Efficiency for Cefoxitin and Inactivation Rates for Tazobactam (original) (raw)

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E240V Substitution Increases Catalytic Efficiency toward Ceftazidime in a New Natural TEM-Type Extended-Spectrum β-Lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens Clinical Isolates

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Multiple substitutions at position 104 of β -lactamase TEM-1: assessing the role of this residue in substrate specificity

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Reclaiming the Efficacy of -Lactam- -Lactamase Inhibitor Combinations: Avibactam Restores the Susceptibility of CMY-2-Producing Escherichia coli to Ceftazidime

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Reclaiming the Efficacy of β-Lactam–β-Lactamase Inhibitor Combinations: Avibactam Restores the Susceptibility of CMY-2-Producing Escherichia coli to Ceftazidime

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Stability of TEM β-lactamase mutants hydrolyzing third generation cephalosporins

Jean-marie Frère

Proteins: Structure, Function, and Genetics, 1995

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Binding of cephalothin and cefotaxime to D-Ala-D-Ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum .beta.-lactamases

Alexandre Kuzin

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Novel plasmid-mediated beta-lactamase from Escherichia coli that inactivates oxyimino-cephalosporins

Yoshimi Matsumoto

Antimicrobial Agents and Chemotherapy, 1988

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Site-directed mutagenesis of beta-lactamase TEM-1. Investigating the potential role of specific residues on the activity of Pseudomonas-specific enzymes

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European Journal of Biochemistry, 1993

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Structural Basis of Activity against Aztreonam and Extended Spectrum Cephalosporins for Two Carbapenem-Hydrolyzing Class D β-Lactamases from Acinetobacter baumannii

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A novel ceftazidime-hydrolysing extended-spectrum -lactamase, CTX-M-54, with a single amino acid substitution at position 167 in the omega loop

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E240V Substitution Increases Catalytic Efficiency toward Ceftazidime in a New Natural TEM-Type Extended-Spectrum -Lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens Clinical Isolates

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Mutational Events in Cefotaximase Extended-Spectrum -Lactamases of the CTX-M-1 Cluster Involved in Ceftazidime Resistance

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Inactivation of the Pseudomonas-Derived Cephalosporinase-3 (PDC-3) by Relebactam

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The Evolution of Cefotaximase Activity in the TEM β-Lactamase

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Kinetic Profile and Molecular Dynamic Studies Show that Y229W Substitution in an NDM-1/L209F Variant Restores the Hydrolytic Activity of the Enzyme toward Penicillins, Cephalosporins, and Carbapenems

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Effect of substitution of Asn for Arg276 in the cefotaxime-hydrolyzing class A β-lactamase CTX-M-4

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Characterization of CTX-M-140, a Variant of CTX-M-14 Extended-Spectrum β-Lactamase (ESBL) with Decreased Cephalosporin Hydrolytic Activity, from Cephalosporin-Resistant Proteus mirabilis

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Evolution of an enzyme activity: crystallographic structure at 2-A resolution of cephalosporinase from the ampC gene of Enterobacter cloacae P99 and comparison with a class A penicillinase

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Effect of substitution of Asn for Arg-276 in the cefotaxime-hydrolyzing class A β-lactamase CTX-M-4

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Effect of substitution of Asn for Arg-276 in the cefotaxime-hydrolyzing class A �-lactamase CTX-M-4

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Cefotaxime, des-Cefotaxime and Ceftazidime: in vitro activity and stability to hydrolysis from TEM-derived extended spectrum beta-lactamases

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Characterization and amino acid sequence analysis of a new oxyimino cephalosporin-hydrolyzing class A β-lactamase from Serratia fonticola CUV

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Mechanism of inhibition of the PC1 .beta.-lactamase of Staphylococcus aureus by cephalosporins: importance of the 3'-leaving group

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