158. Gene Therapy for Chronic Pain Control: Perspectives of HSV1 Mediated Gene Transfer to Supraspinal Centres (original) (raw)

158. Gene Therapy for Chronic Pain Control: Perspectives of HSV1 Mediated Gene Transfer to Supraspinal Centres

Molecular Therapy, 2005

Abstract

Subcutaneous application of Herpes Simplex Virus type 1 (HSV-1) vectors mediating enkephalin transfer to the sensory neurons of the dorsal root ganglia, were shown to induce analgesia and reduce hyperalgesic reactions. These results prompted to use these vectors in the ...

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