Effect of the G-308A polymorphism of the tumor necrosis factor α gene on the risk of ischemic heart disease and ischemic stroke: A meta-analysis (original) (raw)

Objective: The G-308A tumor necrosis factor (TNF) α gene variant has been associated with obesity, insulin resistance, and hypertension. We performed a systematical review of the literature by means of a meta-analysis to assess the association of the G-308A TNFα polymorphism with the components of the metabolic syndrome.Research Methods and Procedures: Studies were identified by searches of the literature for