Chondrosarcoma of body of the mandible (original) (raw)

Chondrosarcoma of the Mandible: A Case Report

Chondrosarcomas are malignant tumours of cartilaginous origin. They range from a well-differentiated growth resembling a benign cartilage tumour to a high-grade malignancy with aggressive local behaviour and the potential to metastasize. Only 5% to 10% of chondrosarcomas are known to occur in the head and neck region. A case of chondrosarcoma of the anterior region of the mandible is presented, along with a review of the relevant literature.

Clinicopathologic correlation of chondrosarcoma of mandible with a case report

Contemporary Clinical Dentistry, 2011

Chondrosarcoma is a rare primary malignant neoplasm of the head, neck, oral and maxillofacial regions. The clinicopathological and radiographic findings are usually characteristic; however, not decisive. The neoplasm is usually treated by wide surgical resection because it is traditionally radioresistant. However, radiotherapy is generally advised for high-grade lesions, and chemotherapy has a palliative role. The treatment and management are primarily guided by the histological grades of the neoplasm. Prognosis of jaw lesions is poor as compared to the lesions affecting the long bones of the body, and the cause of death is usually by direct extension in the base of the skull or due to distant metastasis to lungs and other bones. A clinical case of chondrosarcoma, involving the right half of mandible of a 36 year old male patient is discussed herewith, encompassing the entire gamut of clinicopathological, radiological and treatment modalities rendered.

Chondrosarcoma of the Anterior Mandible

Asian Journal of Oral and Maxillofacial Surgery, 2008

Chondrosarcomas are malignant tumours of cartilaginous origin. Chondrosarcomas are rarely found in the jaw bones. Their presentation may vary from a well-differentiated lesion to a high-grade malignancy with aggressive local behaviour and potential to metastasise. The clinical and radiographic features are similar to those seen in other jaw tumours, often delaying diagnosis and treatment. We report a patient with chondrosarcoma of the anterior mandibular region, who was treated with segmental resection and reconstruction. No signs of recurrence or distant metastasis have been observed at the 1-year follow-up.

Chondrosarcoma of the Mandible -A Rare Case Report

https://www.ijhsr.org/IJHSR\_Vol.6\_Issue.3\_March2016/44.pdf, 2016

Chondrosarcomas are the third most common malignant bone neoplasm. It has now been recognized that it is not a stereotypical disease but has variants. Although any portion of the skeleton may be affected, those involving the jawbones and the skull are decidedly unusual. A conventional chondrosarcoma of retro molar region in a 51-year-old female patient has been reported here.

Chondrosarcoma of the Posterior Mandible: A Case Report

Chondrosarcoma is a malignant tumor of long bones which is characterized by the formation of cartilage. It is the second most common tumor of bones after osteosarcoma and only 3-10% of cases occur in maxillofacial region. Chondrosarcomas mostly occur in individuals older than 50 years with maxilla being the most common site of involvement in maxillofacial skeleton. Involvement of mandible is very rare and mostly anterior portion is involved. A rare case of chondrosarcoma of the left posterior mandible in a 21 year old female patient is presented and review of literature is discussed.

Case report: Chondrosarcoma of the head and neck

Human Pathology: Case Reports, 2017

Chondrosarcoma originates in the bones of the head and neck. It is an unusual neoplasm that is slow-growing and represents only 1-3% of all cases of chondrosarcoma. Here, we report a case of a 45year-old male Caucasian patient treated at Hospital Amaral Carvalho with a history of swelling of the face and a tumoral mass in the right maxilla with infiltration into the skin, which had been present for 4 months. A computerized tomography (CT) of the face and sinuses demonstrated a lesion in the right maxilla. A maxilectomia without orbital exenteration was performed. It was diagnosed as a grade III chondrosarcoma, with infiltration into the subjacent bone, anterior wall of the maxillary sinus and floor of the orbit. The patient presented with recurrence of the tumor after adjuvant therapies. A molecular study on the present case showed an unusually large number of abnormalities. This finding demonstrated extreme chromosomal instability, which was likely due to the undifferentiation of the tumor. Although there are no cases in the literature with which to compare, these findings may elucidate potential therapeutic targets for advanced tumors without other therapeutic options.

Mesenchymal Mandibular Chondrosarcoma: A Case Report and Review of Literature

Open Journal of Stomatology

Introduction: Chondrosarcomas (CS) are malignant cartilaginous tumors of rare maxillary localization. Their evolution is generally slow in time. They have a high tendency for locoregional recurrence after surgical treatment. Their prognosis depends on their degree of differentiation and the quality of resection. The authors report a clinical case of mesenchymal mandibular chondrosarcoma (MC), which is considered to be a subtype of CS, and specify the epidemiological, diagnostic, therapeutic and evolutionary features of this tumor. Case Report: A 73-year-old woman reported in February 2018 in our department complained of a slowly enlarging mass involving the right part of the lower jaw for the last 18 months. On examination a firm multilobular painful mass was palpated with cortical expansion, occupying the right side. A CT scan with 3D reconstruction was achieved and showed osteolysis lesions and cortical thickening. The mass biopsy for histological examination found a grade I well-differentiated bone chondrosarcoma. We performed a hemi-mandibulectomy with complete resection of the tumor. The anatomopathologic examination of the resection specimen was in favour of a grade II mesenchymal chondrosarcoma. No radiotherapy was needed. The patient's follow up was uneventful. Discussion: CS grading is the key to its management. Low grade CS (grades I and II) of the facial skeleton are luckily the most common, they are best treated with a local resection using 1.5 cm margins for bone and soft tissue. According to published literature, CS was historically considered as a radio resistant tumor. Radiotherapy and chemotherapy were therefore mainly reserved for high-grade tumors and for non-operable lesions. However, radical local surgery appears to be the treatment of choice for low grade chondrosarcoma. Conclusion: CS's definitive diagnosis depends on appropriate radiographic evaluation along with adequate biopsy with meticulous histopathological examination and adjunctive immunohistochimical analysis. Neither chemotherapy nor radiotherapy is indicated as primary treatment. A long period follow-up should be advised as recurrence How to cite this paper: Abouchadi, A.,

Mesenchymal Chondrosarcoma of the Mandible

Asian Journal of Oral and Maxillofacial Surgery, 2008

This report describes a 33-year-old man diagnosed with mesenchymal chondrosarcoma. The patient was referred with a painless, elastic hard mass in the retromolar region. Radiologically, the tumour presented as an expansion of the right mandibular ramus partly extending to the inferior masseter. A segmental mandibulectomy was performed during the initial surgery. Histopathologically, the tumour showed well-differentiated hyaline cartilage tissue in the lobules with cartilaginous islands and small cells. Immunohistochemically, the tumour cells reacted positively to clusters of differentiation99 and S-100 protein. The tumour recurred in the right inferior temporal fossa 3 years after the initial surgery. Although radical right maxillectomy and dissection of the inferior temporal fossa were carried out immediately, the patient developed multiple pulmonary metastases after 10 months.

Mesenchymal chondrosarcoma of mandible

Journal of Oral and Maxillofacial Pathology, 2016

Mesenchymal chondrosarcomas (MC) are rare and aggressive forms of chondrosarcoma. They are distinct tumors arising in unicentric or multicentric locations from both skeletal and extraskeletal tissues. The most affected region is the facial skeleton, especially the jaws. In this report, we present a case of MC primarily involving the mandible in a 60-year-old female patient.