Susceptibility of Human Malaria Parasites to Chloroquine is pH Dependent (original) (raw)

Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum

Timothy Geary

Biochemical Pharmacology, 1986

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Identification of acid compartment of Plasmodium falciparum infected human erythrocytes as the target of the antimalarial drug chloroquine

Ioav Cabantchik

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Accumulation of chloroquine by membrane preparations from Plasmodium falciparum

Paul Schlesinger

Molecular and Biochemical Parasitology, 1990

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Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter

S. Bröer

Science, 2009

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Kinetic modelling of the response of Plasmodium falciparum to chloroquine and its experimental testing in vitro

Timothy Geary

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Chloroquine exposure triggers distinct cellular responses in sensitive versus resistant Plasmodium falciparum parasites

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Uptake and efflux of chloroquine by chloroquine-resistant Plasmodium falciparum clones recently isolated in Africa

Hamza Babiker

Acta Tropica, 1994

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On the Mechanism of Chloroquine Resistance in Plasmodium falciparum

Paolo Marcatili

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Evidence for electrogenic accumulation of mefloquine by malarial parasites

Yongyuth Yuthavong

Biochemical Pharmacology, 1988

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THE DIFFERING IMPACT OF CHLOROQUINE AND PYRIMETHAMINE/SULFADOXINE UPON THE INFECTIVITY OF MALARIA SPECIES TO THE MOSQUITO VECTOR

Ricardo Thompson

1998

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Inoculum effect with chloroquine and Plasmodium falciparum

Paul Schlesinger

Antimicrobial agents and …, 1987

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Chloroquine and desethylchloroquine concentrations in blood cells and plasma from Indian patients infected with sensitive or resistantPlasmodium falciparum

Sarala Subbarao

Annals of Tropical Medicine & Parasitology, 2000

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Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum

David Fidock

Molecular Microbiology, 2007

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Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum

Peter Madrid

Biochemical Pharmacology, 2007

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Stage-Dependent Effects of Chloroquine on Plasmodium falciparum In Vitro 1

Timothy Geary

The Journal of Protozoology, 1983

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Determination of chloroquine and desethylchloroquine in plasma and blood cells of Plasmodium vivax malaria cases using liquid chromatography

Virendra Dua

Journal of Pharmaceutical and Biomedical Analysis, 1999

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Evidence for a pfcrt -Associated Chloroquine Efflux System in the Human Malarial Parasite Plasmodium falciparum †

David Fidock

Biochemistry, 2005

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Degrees of chloroquine resistance in Plasmodium - Is the redox system involved?

David Fidock

International Journal for Parasitology: Drugs and Drug Resistance, 2012

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In vitro response of Kenyan Plasmodium falciparum to chloroquine in different media

Davy Koech

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1985

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Interaction between chloroquine and diverse pharmacological agents in chloroquine resistant Plasmodium yoelii nigeriensis

Naresh Singh

Acta Tropica, 2000

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Antagonism of chloroquine with other antimalarials

Pierre Druilhe

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988

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In Vitro Increase in Chloroquine Accumulation Induced by Dihydroethano- and Ethenoanthracene Derivatives in Plasmodium falciparum-Parasitized Erythrocytes

Daniel Parzy, Thierry Fusai

Antimicrobial Agents and Chemotherapy, 2002

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Ex Vivo Drug Susceptibility of Ferroquine against Chloroquine-Resistant Isolates of Plasmodium falciparum and P. vivax

Kim Piera

Antimicrobial Agents and Chemotherapy, 2011

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Population Pharmacokinetics and Pharmacodynamics of Chloroquine in a Plasmodium vivax Volunteer Infection Study

Stephan Chalon

Clinical Pharmacology & Therapeutics, 2020

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Pharmacokinetics, Pharmacodynamics, and Allometric Scaling of Chloroquine in a Murine Malaria Model

Kevin Batty

Antimicrobial Agents and Chemotherapy, 2011

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The effects of α 1 -acid glycoprotein on the reversal of chloroquine resistance in Plasmodium falciparum

Ayoade Oduola

Annals of Tropical Medicine & Parasitology, 2006

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In vitro sensitivity pattern of chloroquine and artemisinin in Plasmodium falciparum

Supriya Sharma

Indian journal of medical microbiology

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Mechanism of malarial haem detoxification inhibition by chloroquine

Amit Pandey

Biochemical Journal, 2001

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Cellular Uptake of Chloroquine Is Dependent on Binding to Ferriprotoporphyrin IX and Is Independent of NHE Activity in Plasmodium falciparum

Omar Janneh

The Journal of Cell Biology, 1999

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