Towards Coleoptera-specific high-throughput screening systems for compounds with ecdysone activity: development of EcR reporter assays using weevil (Anthonomus grandis)-derived cell lines and in silico analysis of ligand binding to A. grandis EcR ligand-binding pocket (original ) (raw )A cell-based reporter assay for screening for EcR agonist/antagonist activity of natural ecdysteroids in Lepidoptera (Bm5) and Diptera (S2) cell cultures, followed by modeling of ecdysteroid-EcR interactions and normal mode analysis
Moisés Zotti
Pesticide Biochemistry and Physiology, 2013
View PDFchevron_right
Properties of ecdysteroid receptors from diverse insect species in a heterologous cell culture system - a basis for screening novel insecticidal candidates
Guy Smagghe
FEBS Journal, 2009
View PDFchevron_right
Characterization and partial cloning of ecdysteroid receptor from a cotton boll weevil embryonic cell line
Tarlochan Dhadialla
Archives of Insect Biochemistry and Physiology, 1997
View PDFchevron_right
High-throughput screening of ecdysone agonists using a reporter gene assay followed by 3-D QSAR analysis of the molting hormonal activity
Guy Smagghe
Bioorganic & Medicinal Chemistry, 2006
View PDFchevron_right
Requirement of co-factors for the ligand-mediated activity of the insect ecdysteroid receptor in yeast
Salam Shaaban
Journal of Molecular Endocrinology, 2001
View PDFchevron_right
Cloning, ligand-binding, and temporal expression of ecdysteroid receptors in the diamondback moth, Plutella xylostella
Xiwu Gao
BMC Molecular Biology, 2012
View PDFchevron_right
Unprecedented conformational flexibility revealed in the ligand-binding domains of the Bovicola ovis ecdysone receptor (EcR) and ultraspiracle (USP) subunits
Tram Phan , George Lovrecz
Acta Crystallographica Section D-Biological Crystallography, 2014
View PDFchevron_right
Molecular cloning, expression analysis and functional confirmation of ecdysone receptor and ultraspiracle from the Colorado potato beetle Leptinotarsa decemlineata
Yoshiaki Nakagawa
Febs Journal, 2005
View PDFchevron_right
An Immunophilin is a Component of the Insect Ecdysone Receptor (EcR) Complex
qisheng song
Insect Biochemistry and Molecular Biology, 1997
View PDFchevron_right
Ecdysone Receptor Present in Insects is a Novel Target for Insecticide
Neeru Redhu
International Journal of Current Microbiology and Applied Sciences, 2018
View PDFchevron_right
Forest insect cell lines responsive to 20-hydroxyecdysone and two nonsteroidal ecdysone agonists, RH-5849 and RH-5992
Arthur Retnakaran
Journal of Insect Physiology, 1995
View PDFchevron_right
Highly Flexible Ligand Binding Pocket of Ecdysone Receptor: A SINGLE AMINO ACID CHANGE LEADS TO DISCRIMINATION BETWEEN TWO GROUPS OF NONSTEROIDAL ECDYSONE AGONISTS
Mitch Polley
Journal of Biological Chemistry, 2004
View PDFchevron_right
Complex steroid-peptide-receptor cascade controls insect ecdysis
Ingrid Zitnanová
General and comparative …, 2007
View PDFchevron_right
Ecdysteroid ligand-receptor selectivity - exploring trends to design orthogonal gene switches
Anna Barlow
FEBS Journal, 2008
View PDFchevron_right
The X-ray Structure of a Hemipteran Ecdysone Receptor Ligand-binding Domain
Dave Winkler
Journal of Biological Chemistry, 2005
View PDFchevron_right
A cell-based high-throughput screening system for detecting ecdysteroid agonists and antagonists in plant extracts and libraries of synthetic compounds
Silvia Ciolfi
Faseb Journal, 2003
View PDFchevron_right
Comparative effects of a non-steroidal ecdysone agonist RH-5992 and 20-hydroxyecdysone in a lepidopteran cell line (IAL-PID2)
Stéphane Debernard
Insect Biochemistry and Molecular Biology, 2005
View PDFchevron_right
Functions of the ecdysone receptor isoform-A in the hemimetabolous insect Blattella germanica revealed by systemic RNAi in vivo
Xavier Belles
Developmental Biology, 2006
View PDFchevron_right
Cloning and Characterization of Ecdysone Receptor and Ultraspiracle cDNAs from Spodoptera litura
Manolis Mavroidis
Annals of the New York Academy of Sciences, 2005
View PDFchevron_right
Structural changes under low evolutionary constraint may decrease the affinity of dibenzoylhydrazine insecticides for the ecdysone receptor in non-lepidopteran insects
Pierre Rouge
Insect Molecular Biology, 2012
View PDFchevron_right
Ecdysteroid signaling in ecdysteroid-resistant cell lines from the polyphagous noctuid pest Spodoptera exigua
Hadi Mosallanejad
Insect Biochemistry and Molecular Biology, 2008
View PDFchevron_right
Comparative toxicity and ecdysone receptor affinity of non-steroidal ecdysone agonists and 20-hydroxyecdysone in Chironomus tentans
Guy Smagghe
Insect Biochemistry and Molecular Biology, 2002
View PDFchevron_right