Epidemiological and histopathological pattern of primary oral carcinomas in Venezuela (original) (raw)
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Carcinoma of Mouth: Retrospective Analysis of 598 Brazilian Patients
2018
Introduction: Mouth cancer is a term that means cancers of the lip and oral cavity (oral mucosa, gingiva, hard palate, oral tongue and floor of the mouth). Oral cancer is more common in some developing countries because it is related to the population lifestyle, particularly with the risk factors contact due to cultural issues and the difficulty accessing treatment. Purpose: The aim of this study is to present occurrence demographic data of patients diagnosed with squamous cell carcinoma in UFMG’s Dentistry School. Patients and Methods: It was analyzed 598 diagnosed clinical charts. Histopathological reports of all patients with diagnosed oral cancer from 1956 to 2010 were analyzed, following inclusion and exclusion criteria. Information about genre, age, skin color, disease time report and injury site was collected and statistical analysis was done in the software Microsoft Excel 2013. Results: The sample consisted of 24, 75% women and 74, 75% men. Regarding skin color, 41, 64% wer...
Epidemiological profile of malignant oral cancers in a population of northern Portugal
Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial, 2016
, with histological confirmation. Data were analyzed according district of residence, gender, age, topographic location of the tumor, histological type, degree of differentiation, and stage (TNM). Results: During this retrospective descriptive study, 1041cases were reported in both genders. Men were more affected than women in a 3:1 proportion. The number of diagnosed oral carcinoma cases increased in the 5th decade of age (19.69% ± 2.42%) and progressively decrease after the 7th (18.35% ± 2.35%). The most affected region was the tongue (C01 + C02) (43.51% ± 3.01%), followed by the floor of the mouth (C04) (17.48% ± 2.31%). The most prevalent histological entity was squamous cell carcinoma (93.37% ± 10.90%) in grade I (44.20% ± 5.86%). Regarding TNM stages, the most frequent was stage IV (42.00% ± 3.89%). Conclusion: The epidemiological profile of oral malignant neoplasms found in our study is in accordance with the existing literature. More epidemiological studies, as well as awareness and prevention programs, should be conducted in this area in Portugal.
Oral malignant tumours: a report on 728 cases in Chile
Acta odontológica latinoamericana : AOL, 2010
The objective of this study was to describe the main clinical characteristics and the relative frequency of each type of oral malignancies received at the Oral Pathology Reference Insti- tute (IREPO) of the Faculty of Odontology; University of Chile, since 1975 to 2006. Studies were performed of 728 cases of biopsies recorded in the IREPO data base with a diagnosis corresponding to some type of Oral Malignant Tumour (OMT) and which counted with all required clinical and demographic data. Histological sec- tions were observed by two oral pathologists with the purpose of confirming the original diagnosis. 61.6% of OMTs were observed in males and 38.4% in females. Patients average age was 65.3 years, and the most frequent localization was the alveolar/gums ridge (20% of the cases) being the squamous cell carcinoma (SCC) the most frequent pathology (58.4%) These results are similar to the frequencies of oral malignancies reported for other countries as to distri- bution per gender, age, histological diagnosis. Nevertheless, frequency distribution of each of the OMTs is different to that indicated in most publications. Key words: mouth neoplasms, squamous cell carcinoma, case reports.
Epidemiological characterization of oral cancer. Literature review
Journal Oral Of Research, 2015
Oral cancer is a disease of high impact globally. It ranks as the sixth more frequent one among all types of cancer. In spite of being a widely known pathology and easy access to the diagnosis, the lack of epidemiological data reported in the last 10 years in Chile called attention to. At the global level, the World Health Organization (WHO) has developed a project called "GLOBOCAN" in order to collect epidemiological data of the global cancer, between its data, highlights the high incidence and high rate of mortality in the male sex, parameter that shows tendency to replicate in both America and Chile. In consequence to these data, a narrative review of the literature concerning the epidemiological profile of the different forms of oral cancer in the past 15 years was done. The diagnosis of oral cancer crosses transversely the Dental Science, forcing us to establish triads of work between oral and maxillofacial surgeons, pathologists and dentists of the various specialties, so as to allow a timely research, appropriate biopsies and histopathological studies finishes with the purpose of, on the one hand, obtain timely and accurate diagnostics, in addition, maintaining the epidemiological indicators.
Oral carcinoma epidemiology in Paraná State, Southern Brazil
Cadernos de Saúde Pública, 2009
Oral carcinoma is the sixth most frequent type of cancer in the world and the seventh most common in Brazil (the country with the highest incidence in Latin America). Mean five-year survival remains one of the lowest among the main cancers, thus justifying studies that contribute to the development of preventive strategies. The aim of this study was to compare the epidemiological, clinical, and histological characteristics of 91 patients with oral carcinoma. Mean age was 58.62 ± 10.46 years, and male-to-female ratio was 6.6:1.0 (79 men and 12 women). European descendants predominated with 79 patients (86.8%). Eightyfive individuals (93.4%) smoked and 70 (76.9%) consumed alcohol regularly. Anatomical distribution of tumors was: 27 (29.7%) tongue; 18 (19.8%) floor of mouth; 11 (12.1%) oropharynx; and 11 (12.1%) oral mucosa. Fifty-seven patients (62.6%) presented lymph node involvement and three (3.3%) had distant metastases. Surgery and radiotherapy were used in 43.2% of patients. With the exception of the male/female ratio (which was higher), our data are consistent with previous studies on oral carcinoma patients.
Clinical features and evolution of oral cancer: A study of 274 cases in Buenos Aires, Argentina
Medicina oral, patología oral y cirugía bucal, 2008
Oral Squamous Cell Carcinoma has a low survival rate, 34 to 66% five-year survival after initial diagnosis, due to late diagnosis. The aim of the present study was to examine the clinical features and evolution of oral cancer in the University of Buenos Aires. 274 patients with primary oral carcinoma, over the 1992-2000 period were included in the study. The survival rate of this population was 80% at 12 months, 60% at 24 months, 46% at 36 months, 40% at 48 months, and 39% at 60 months (5 years). The tumor localizations with worse prognosis were floor of mouth and tongue, with survival rates of 19% and 27% respectively. Sixty-five percent of the oral carcinomas evaluated were diagnosed at advanced stages (III and IV). The patients under study exhibited the lowest survival rate described for oral cancer (34% five-year survival after initial diagnosis). The population included in this study can be considered representative of the Argentine population. This bad prognosis would be mainl...
Oral Cancer Detection: A Comparative Study In Argentina
2013
Oral Squamous Cell Carcinoma has a low survival rate, 34 to 66% five-year survival after initial diagnosis, due to late diagnosis. Objetives: The aim of the present study was to examine the clinical features and evolution of oral cancer in the University of Buenos Aires. Study design: 274 patients with primary oral carcinoma, over the 1992-2000 period were included in the study. Results: The survival rate of this population was 80% at 12 months, 60% at 24 months, 46% at 36 months, 40% at 48 months, and 39 % at 60 months (5 years). The tumor localizations with worse prognosis were floor of mouth and tongue, with survival rates of 19% and 27% respectively. Sixty-five percent of the oral carcinomas evaluated were diagnosed at advanced stages (III and IV). Conclusions: The patients under study exhibited the lowest survival rate described for oral cancer (34% five-year survival after initial diagnosis). The population included in this study can be considered representative of the Argentine population. This bad prognosis would be mainly due to the large number of oral cancer cases that were diagnosed at advanced stages.
Epidemiological study of oral cancer�patients in Alava province, Spain
Experimental and Therapeutic Medicine, 2011
The authors conducted a retrospective study of oral squamous cell carcinoma (OSSC) patients in the province of Alava, Spain, to investigate the various epidemiological factors involved. The study included data on 30 patients referred to the Otolaryngology Department of our hospital. The authors identified epidemiological data, including age, symptoms, localization, tumor size, risk factors, tumor stage, treatment and outcome. An elevated percentage of risk factors was found, underlining the importance of early diagnosis. The highest prevalence was in the sixth decade of life. The most frequent symptom was pain, and the localization was in the tongue in 70% of cases. Tumor size ranged from 2 to 3 cm, and 85% of patients underwent surgical resection. Risk factors of smoking and drinking affected 50% of the patients.
Medicina Oral Patología Oral y Cirugia Bucal, 2011
Objective. To establish the time trends of the frequency and prevalence of oral cavity cancer in regard to age and gender in a 20-years (time period 1989-2008) cohort of Mexicans. Design and Setting. 13,235 head and neck biopsies from the archive of the Oral Pathology Laboratory, Dental School, National Autonomous University of Mexico were revised. The cases with diagnoses of oral cancer were selected. Gender and age at diagnosis was obtained from medical records. The frequency and prevalence of oral cavity cancer and oral squamous cell carcinoma were assessed biannually in regard to the total number of population served by the oral pathology laboratory. The statistical significance of trends was established using the linear logistic regression (curve estimation) test (s 0.05). Results. 298 cases (138 males; 160 females) of oral cancer were included; 167 (92 females; 75 males; female:male ratio: 1.1:1) corresponded to oral squamous cell carcinoma. From 1989 to 2008 the prevalence of oral cancer and oral squamous cell carcinoma increased 200% (s 0.05) and 100% (s 0.000) respectively. The increase of frequency and prevalence was observed in both genders however only in females was significant (s 0.000). We do not identify changes in the age at diagnosis. Conclusions. Oral cancer, specifically oral squamous cell carcinoma, has increase in Mexicans females in the last 20 years.
Medicina oral, patología oral y cirugía bucal, 2006
Malignant neoplasm (MN) mortality worldwide ranks among the first four causes of death, in the 1990 decade (1-4). The aim of this work is to study the eight most frequent MN mortality rates, and especially that one caused by oral cancer (OC) in the province of Cordoba, Argentine Republic, in the period between 1975 and 2000, in order to analyze its characteristics and compare with other populations in America and Europe. The data were provided by the provincial and national Health Ministry and Globocan 2000. The highest male rates were those of Slovakia and France, prevailing lung and bronchus tumors; whereas in females the highest rate was that of breast cancer in the United Kingdom and Germany, and lung cancer in the United States. Regarding to OC in the populations under study, Slovakia and France held the highest rates for both sexes, being Cordoba and Argentina among the lowest values, especially in women. Tongue was the most frequent site in Cordoba (43.5%), followed by saliva...