Protein kinase A and its role in human neoplasia: the Carney complex paradigm (original) (raw)
Molecular Analysis of the Cyclic AMP-Dependent Protein Kinase A (PKA) Regulatory Subunit 1A (PRKAR1A) Gene in Patients with Carney Complex and Primary Pigmented Nodular Adrenocortical Disease (PPNAD) Reveals Novel Mutations and Clues For Pathophysiology: Augmented PKA Signaling is Associated with...
Constantine Stratakis
The American Journal of Human Genetics, 2002
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Human tumors associated with Carney complex and germline PRKAR1A mutations: a protein kinase A disease!
Sotirios Stergiopoulos
FEBS Letters, 2003
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PRKACA: the catalytic subunit of protein kinase A and adrenocortical tumors
Constantine Stratakis
Frontiers in cell and developmental biology, 2015
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A Large Family with Carney Complex Caused by the S147G PRKAR1A Mutation Shows a Unique Spectrum of Disease Including Adrenocortical Cancer
Constantine Stratakis
The Journal of Clinical Endocrinology & Metabolism, 2012
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Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex
Christoforos Giatzakis
Nature Genetics, 2000
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17Q22-24 Chromosomal Losses and Alterations of Protein Kinase a Subunit Expression and Activity in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia
Fabiano Sandrini
The Journal of clinical endocrinology and metabolism, 2006
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Clinical and molecular genetics of primary pigmented nodular adrenocortical disease
Fabiano Sandrini
Arquivos Brasileiros de Endocrinologia & Metabologia, 2004
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Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex
Lawrence Kirschner, Svetlana Pack
Nature genetics, 2000
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atualiza��o Clinical and Molecular Genetics of Primary Pigmented Nodular Adrenocortical Disease
Fabiano Sandrini
2004
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Carney complex and other conditions associated with micronodular adrenal hyperplasias
Constantine Stratakis
Best Practice & Research Clinical Endocrinology & Metabolism, 2010
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PRKACB variants in skeletal disease or adrenocortical hyperplasia: effects on protein kinase A
Edra London
Endocrine-Related Cancer, 2020
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Clinical and molecular genetics of Carney complex
Constantine Stratakis
Best Practice & Research Clinical Endocrinology & Metabolism, 2010
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Absence of PRKAR1A loss of heterozygosity in laser-captured microdissected pigmented nodular adrenocortical tissue from a patient with Carney complex caused by the novel nonsense mutation p.Y21X
Luciana Brito
Arquivos Brasileiros de Endocrinologia & Metabologia, 2008
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Genetics of micronodular adrenal hyperplasia and Carney complex
Nuria Valdés
La Presse Médicale, 2018
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Protein kinase A defects and cortisol-producing adrenal tumors
Constantine Stratakis
Current opinion in endocrinology, diabetes, and obesity, 2015
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A Novel PRKAR1A Mutation Identified in a Patient with Isolated Primary Pigmented Nodular Adrenocortical Disease
Objoon Trachoo
Case Reports in Oncology, 2017
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A novel mutation in PRKAR1A gene in a patient with Carney complex presenting with pituitary macroadenoma, acromegaly, Cushing's syndrome and recurrent atrial myxoma
Neda Behzadnia
Archives of endocrinology and metabolism, 2021
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Primary pigmented nodular adrenocortical disease reveals insulin-like growth factor binding protein-2 regulation by protein kinase A
Adda Grimberg
Growth hormone & IGF research, 2007
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PRKAR1A, one of the Carney complex genes, and its locus (17q22-24) are rarely altered in pituitary tumours outside the Carney complex
Fabiano Sandrini
Journal of Medical Genetics, 2002
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Mutations in regulatory subunit type 1A of cyclic adenosine 5'-monophosphate-dependent protein kinase (PRKAR1A): phenotype analysis in 353 patients and 80 different genotypes
Constantine Stratakis
The Journal of clinical endocrinology and metabolism, 2009
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Novel Somatic Mutations in the Catalytic Subunit of the Protein Kinase A as a Cause of Adrenal Cushing's Syndrome: A European Multicentric Study
Giorgio Arnaldi
The Journal of Clinical Endocrinology & Metabolism, 2014
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Called and uncalled for functions of the main catalytic subunit of protein kinase A: one enzyme, many faces
Constantine Stratakis
Endocrinology, 2019
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PKA regulatory subunit 1A inactivating mutation induces serotonin signaling in primary pigmented nodular adrenal disease
Constantine Stratakis
JCI Insight, 2016
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Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity
Sotirios Stergiopoulos, Thalia Bei
Cancer research, 2003
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Carney Complex: an update
Paraskevi Salpea
European journal of endocrinology / European Federation of Endocrine Societies, 2015
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The Transcriptome that Mediates Increased Cyclic Adenosine Monophosphate Signaling in Prkar1a Defects and Other Settings
Constantine Stratakis
Endocrine Practice, 2011
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E pluribus unum? The main protein kinase A catalytic subunit (PRKACA), a likely oncogene, and cortisol-producing tumors
Constantine Stratakis
The Journal of clinical endocrinology and metabolism, 2014
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