Bovine Colostrum as a Natural Growth Factor (original) (raw)
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Bovine colostrum as a natural growth promoter for newly weaned piglets: a review
2008
The aim of this review is to present the potential of bovine colostrum as growth promoter in piglet-weaner diet. The main consequence of weaning the piglet is a critical period of underfeeding of which results in the so-called "weaning growth check". Near this reduction in feed intake and growth performance, the gastro-intestinal tract and the immune system of the animal are also affected. Bovine colostrum can be used to reduce the impact of weaning by the action of its bioactive components which may be classified in two classes: the growth factors, which promote the growth and development of the newborn, and the antimicrobial factors, which provide passive immunity and protect against infection. Studies using bovine colostrum in the weaning diet showed increased growth performance and feed intake the first week post-weaning, moreover, a better feed efficiency was also reported, suggesting that the growth benefits attributed to the bovine colostrum supplementation is not due solely to the increased feed consumption. Effects were also observed on the intestinal tract (gastric pH, mucosa restoration, intestinal microflora, local immunisation) but the systemic immune responses were not altered.
Bovine colostrum as a natural growth factor for newly-weaned piglets: a review
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Animal Science and Biotechnologies, 2009
The aim of this review is to present the potential of bovine colostrum as growth promoter in piglet-weaner diet. The main con sequence of weaning the piglet is a critical period of underfeeding of which results in the so-called “weaning growth check”. Near this reduction in feed intake and growth perfo rmance, the gastro-intestinal tract and the immune system of the animal are also affected. Bovi ne colostrum can be used to reduce the impact of weaning by the action of its bioactive co mponents which may be classified in two classes: the growth factors, which promote the gro wth and development of the newborn, and the antimicrobial factors, which provide passive im munity and protect against infection. Studies using bovine colostrum in the weaning diet showed increased growth performance and feed intake the first week post-weaning, moreov er, a better feed efficiency was also reported, suggesting that the growth benefits attri buted to the bovine colostrum supplementation is not due...
Journal of Animal Science, 2012
The present study investigated the effect of 3 different durations of feeding a diet supplemented with defatted bovine colostrum (Col) on growth performance and sanitary status of the weaned piglet. At 28 d of age, piglets were weaned and fed 1 of the 2 following diets: a control (Ctrl) starter diet or a starter diet supplemented with Col. Two experiments were conducted. In Exp. 1, 310 piglets (12 pens consisting of 10 piglets/pen and 10 pens consisting of 19 piglets/pen) were allocated to 1 of the 2 dietary treatments for 12 d. In Exp. 2, 522 piglets (18 pens consisting of 10 piglets/pen and 18 pens consisting of 19 piglets/pen) were allocated to 1 of the following 3 dietary treatments: fed the Ctrl diet from d 1 to 12 (Ctrl), Col diet from d 1 to 4 and then the Ctrl diet up to d 12 (Col-4d), or the Col diet from d 1 to 6 and then the Ctrl diet up to d 12 (Col-6d). For both experiments, a commercial second-phase diet was fed to piglets from d 12 to 46. Feed intake, growth performance, and cleanliness of fl oor and hindquarters of animals were investigated during the fi rst 7 wk postweaning. In Exp.
Effect of a bovine colostrum whey supplementation on circulating hormones in weaned piglets
2008
This study examined the effect of a bovine colostrum whey supplementation on growth performance, feed intake, faecal Escherichia coli population and systemic immune response of piglets at weaning. A total of 96 piglets weaned at 26 6 2 days of age were assigned for 4 weeks to one of the two treatments: (1) the control (commercial diet with bovine milk whey powder) and (2) the colostrum (commercial diet with freeze-dried bovine colostrum whey) treatments. The two supplements were incorporated in the diet at a level of 20 g/kg during the first 2 weeks after weaning and lowered to a level of 10 g/kg for the next 2 weeks. BW and feed intake were measured weekly. Faecal E. coli counts were determined weekly on specific culture media. Blood samples were collected weekly and submitted to a cell counter analyser for their main components (red and white blood cells, platelets) and flow cytometry was used to determine the lymphocyte population (B, T, T h and T c). Finally, total seric immunoglobulin (IgM, IgG and IgA) concentrations were determined by the ELISA method. During the first week of the trial, the piglets from the colostrum treatment had improved average daily gain (170 g/day v. 81 g/day, P , 0.001), average daily feed intake (346 g/day v. 256 g/day, P 5 0.03) and feed efficiency (BW gain/feed intake) (0.48 v. 0.31, P 5 0.04). The pigs fed the colostrum treatment had also a 25% increase in circulating IgA (P 5 0.03) compared with the control treatment the first week. It is concluded that a distribution of bovine colostrum whey (20 g/kg diet) during the first week post-weaning induces a systemic IgA response and has a beneficial action on growth performances and feed efficiency.
animal, 2008
This study examined the effect of a bovine colostrum whey supplementation on growth performance, feed intake, faecal Escherichia coli population and systemic immune response of piglets at weaning. A total of 96 piglets weaned at 26 6 2 days of age were assigned for 4 weeks to one of the two treatments: (1) the control (commercial diet with bovine milk whey powder) and (2) the colostrum (commercial diet with freeze-dried bovine colostrum whey) treatments. The two supplements were incorporated in the diet at a level of 20 g/kg during the first 2 weeks after weaning and lowered to a level of 10 g/kg for the next 2 weeks. BW and feed intake were measured weekly. Faecal E. coli counts were determined weekly on specific culture media. Blood samples were collected weekly and submitted to a cell counter analyser for their main components (red and white blood cells, platelets) and flow cytometry was used to determine the lymphocyte population (B, T, T h and T c). Finally, total seric immunoglobulin (IgM, IgG and IgA) concentrations were determined by the ELISA method. During the first week of the trial, the piglets from the colostrum treatment had improved average daily gain (170 g/day v. 81 g/day, P , 0.001), average daily feed intake (346 g/day v. 256 g/day, P 5 0.03) and feed efficiency (BW gain/feed intake) (0.48 v. 0.31, P 5 0.04). The pigs fed the colostrum treatment had also a 25% increase in circulating IgA (P 5 0.03) compared with the control treatment the first week. It is concluded that a distribution of bovine colostrum whey (20 g/kg diet) during the first week post-weaning induces a systemic IgA response and has a beneficial action on growth performances and feed efficiency.
Czech Journal of Animal Science, 2017
Supplementation of bovine colostrum (BC) has shown to improve growth performance, intestinal development, and immune response in early-weaned pigs. Little is known about whether BC may have similar effects in neonatal piglets. In the present study, the effect of BC supplementation on mortality, growth performance, and blood parameters (plasma proteins and white blood count) of suckling piglets in the first 10 days of life was investigated under practical conditions with special emphasis on low birth weight piglets. In total, 258 newborn piglets from 30 multiparous sows in a commercial breeding unit were randomly assigned to two different treatment groups. Piglets received either 1 ml of BC orally on days 1–3 of life (group BC, n = 128) or 1 ml of saline (0.9%) (control (CON) group; n = 130). Body weight was measured on days 1, 4, and 10 of life. Blood was collected on days 1 and 4 from 60 piglets per group. No differences in mortality, body weight, and average daily weigh...
Effect of bovine colostrum supplementation on cytokine mRNA expression in weaned piglets
Livestock Science, 2007
The aim of this study was to evaluate the influence of bovine colostrum supplementation on the immune Th1/Th2 response in weaned piglets. After weaning at 21 d, 3 groups of 7 piglets were fed ad libitum with a starter diet and received daily 0, 1 or 5 g of spray-dried bovine colostrum. Spleen and gut-associated lymphoid tissues (GALT): ileal Peyer's patch (iPP), jejunum wall (JW) and mesenteric lymph node (MLN)) biopsies were collected on each piglet after 3 wk of treatment and analysed for their cytokine mRNA expression (IL-2, IL-4, IL-10, IL-12 and IFN-γ) by RT-PCR. The supplementation with bovine colostrum induced an increase (P<0.05) in IL-12 in the JW, in IL-2, IL-10 and IL-12 in the MLN and in IL-4, IL-10 and IL-12 in the iPP. In the latter, bovine colostrum also decreased IFN-γ production (P<0.01). Finally, no effect of the treatments was recorded in the spleen. These results suggest an immunomodulatory effect of bovine colostrum on the GALT, which responded by producing at different levels both Th1 pro-inflammatory cytokines (IL-2, IFN-γ and IL-12) and Th2 anti-inflammatory cytokines (IL-4 and IL-10). This Th1/ Th2 bipolar response protects the weaned piglets from both allergic (food) and infectious (pathogens) diseases.
2010
This study examined the effect of a bovine colostrum supplementation on growth performance, feed intake and the hormonal response of piglets at weaning. Ninety-six newly-weaned piglets were assigned for four weeks to one of the two treatments: Control (diet with bovine milk whey) and Colostrum (diet with bovine colostrum whey) treatments. The supplements were incorporated in a commercial diet at 20 g/kg during the first 2 weeks after weaning and lowered to 10 g/kg for the next 2 weeks. Body weight and feed intake were measured weekly. Blood samples were taken weekly for determination of circulating IGF-I, its binding proteins and the thyroid hormones (T 3 and T 4). During the first week of the trial, the Colostrum-fed piglets presented improved growth performance, feed intake and feed efficiency and a higher concentration in circulating IGF-I (+15 %) compared to the Control piglets. In both treatments, the circulating thyroid hormones were reduced by weaning and the levels measured at weaning were recovered earlier by the Colostrum-fed piglets compared to the Control group (P<0.05). It is concluded that hormonal response observed after the bovine colostrum supplementation is, at least in part, consequent of the positive action of bovine colostrum on the feed intake.