Stem cell transplantation and functional recovery after spinal cord injury: a systematic review and meta-analysis (original) (raw)
SCI [1]. There is no recognized cure for treating SCI and most of the therapeutic modalities are focused on symptomatic relief [2, 3]. Approximately 90% of patients with SCI suffer from long-term motor dysfunctions and the disease related complications. These consequences impose substantial financial and emotional burdens either directly or indirectly. Currently, in most centers, pharmacotherapy has been used for treating spinal cord injuries that has minimal impact on the functional recovery and neuropathic pain symptoms. On the other hand, putting the patient on multiple medications can lead to adverse consequences in long term [4, 5]. Following a SCI, motor dysfunction will persist unless the injured region is recovered. However, neurogenesis is an uncommon phenomenon in the central nervous system (CNS)
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