Supramolecular Aggregates of Water Soluble Dendritic Polyglycerol Architectures for the Solubilization of Hydrophobic Compounds (original) (raw)
2010, Macromolecular Rapid Communications
AI-generated Abstract
This research focuses on synthesizing dendritic polyglycerol architectures that solubilize hydrophobic drugs, achieving significant improvements in solubilization capacity. The core of the polyglycerol is modified to enhance hydrophobicity, yielding amphiphilic structures capable of enabling solubilization of compounds such as pyrene and nimodipine in aqueous environments. Characterization techniques, including UV spectroscopy, indicate the formation of supramolecular aggregates and controlled self-assembly in the studied systems.
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