5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer (original) (raw)
Clinical pharmacokinetic study of 5-FU in continuous 5-day infusions for head and neck cancer
Antoine Thyss, Maurice Schneider
Cancer Chemotherapy and Pharmacology, 1986
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DPD-based adaptive dosing of 5-FU in patients with head and neck cancer: impact on treatment efficacy and toxicity
Cedric Mercier, Bruno Lacarelle
Cancer Chemotherapy and Pharmacology, 2011
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Clinical impact of pharmacokinetically-guided dose adaptation of 5-fluorouracil: results from a multicentric randomized trial in patients with locally advanced head and neck carcinomas
F. Rolland
Clinical cancer research : an official journal of the American Association for Cancer Research, 1998
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Improved complete response rate and survival in advanced head and neck cancer after three-course induction therapy with 120-hour 5FU infusion and cisplatin
John Jacobs
Cancer, 1985
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Treatment Outcome of Pharmacokinetics-Based Dosing of Docetaxel and Fluorouracil in Advanced Head and Neck Cancer Patients
Tarek Shouman
Journal of Cancer Therapy
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A phase II evaluation of a 3-hour infusion of paclitaxel (P), cisplatin (CDDP) & 5-fluorouracil (5FU) in patients with advanced or recurrent squamous cell carcinoma of the head & neck (SCCHN): A Southwest Oncology Group Study
Wolfram Samlowski
Journal of Clinical Oncology, 2004
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Systemic Chemotherapy with Cisplatin Plus 5-FU (PF) for Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (R/M SCCHN): Efficacy and Safety of a Lower Dose of PF (80/800) at a Single Institution in Japan
Naomi Kiyota
Japanese Journal of Clinical Oncology, 2009
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Head and neck irradiation modulates pharmacokinetics of 5-fluorouracil and cisplatin
Mei-ling Hou
Journal of Translational Medicine, 2013
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A phase II evaluation of a 3-hour infusion of paclitaxel, cisplatin, and 5-fluorouracil in patients with advanced or recurrent squamous cell carcinoma of the head and neck
Stephen Williamson
Cancer, 2006
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Feasibility of concurrent chemoradiotherapy with high-dose cisplatin after induction TPF chemotherapy in head and neck cancer: a critical review of the literature and the experience of the European Institute of Oncology
Giuseppe Fanetti
Medical Oncology, 2017
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Superior clinical response and survival rates with initial bolus of cisplatin and 120 hour infusion of 5-fluorouracil before definitive therapy for locally advanced head and neck cancer
John Jacobs
American Journal of Surgery, 1984
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Adaptive intrapatient dose escalation of cisplatin in patients with advanced head and neck cancer
Marc Maliepaard
Anti-Cancer Drugs, 2001
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Concurrent radiotherapy and continuous ambulatory infusion 5-fluorouracil in advanced head and neck cancer
Kailash Narayan
European Journal of Cancer, 1996
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Neoadjuvant therapy for advanced head and neck cancer with allopurinol-modulated high dose 5-fluorouracil and cisplatin a phase I-II study
David Shimm
Cancer, 1987
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Pharmacokinetic-Based Chemotherapy Dosing in Advanced Head and Neck Cancer: A Mini Review
Ahmed Abo Gabal
Research in Oncology, 2019
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Comparison of acute toxicities of two chemotherapy schedules for head and neck cancers
Subramania Iyer
Journal of Cancer Research and Therapeutics, 2006
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Comparative Study of Weekly and Three Weekly Chemoradiation Regimen in Advanced Head and Neck Cancer at Silchar Medical College
Yousuf Choudhury
International Journal of Science and Research (IJSR), 2017
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Comparison of Safety and Efficacy of Two Different Chemotherapy Dosing Schedules Used in Concurrent Chemoradiation of Head and Neck Cancer: A Retrospective Experience from a Tertiary Cancer Care Institute of Eastern India
Palas De
Asian Pacific journal of cancer care, 2023
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An alternative approach with a low dose and prolonged chemotherapy for palliative treatment of locally advanced, metastatic or recurrent squamous cell head and neck cancer
david Reisman
Applied Cancer Research
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Dose Escalation Study of Nedaplatin with 5-Fluorouracil in Combination with Alternating Radiotherapy in Patients with Head and Neck Cancer
H. Tachibana
Japanese Journal of Clinical Oncology, 2007
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Weekly 5-fluorouracil and folinic acid plus escalating doses of cisplatin with glutathione protection in patients with advanced head and neck cancer
R. Valenza
Medical oncology and tumor pharmacotherapy, 1992
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Induction chemotherapy with cisplatin/docetaxel versus cisplatin/5-fluorouracil for locally advanced squamous cell carcinoma of the head and neck: A randomised phase II study
Antonio Rueda Lara
European Journal of Cancer, 2005
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Toxicity of two cisplatin-based radiochemotherapy regimens for the treatment of patients with stage III/IV head and neck cancer
Steven Schild
Head & Neck, 2008
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Toxicity and preliminary results from a trial of hyperfractionated radiation with or without simultaneous 5-fluorouracil-cisplatin in advanced head and neck squamous cell carcinomas
Harold Pillsbury
Seminars in Radiation Oncology
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No effect of dose, hepatic function, or nutritional status on 5-FU clearance following continuous (5-day), 5-FU infusion
François Demard
British Journal of Cancer, 1992
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