The exon junction complex: A splicing factor for long intron containing transcripts? (original) (raw)

The exon junction complex (EJC) plays a crucial role in the splicing of precursor mRNA by binding to the mRNA during splicing and influencing post-splicing events like mRNA stability and translation. Recent studies indicate that the EJC is specifically recruited to certain pre-mRNAs, particularly long intron-containing transcripts, and its interactions can modulate splicing efficiency. Understanding the functions of the EJC may reveal insights into alternative splicing and the regulation of gene expression.