A Pre Induction Administration of One Gram Oral or Intravenous Acetaminophen in Control of Post-Operative Pain: A Comparative Study (original) (raw)
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Pain practice : the official journal of World Institute of Pain, 2012
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Pain is a problem that humanity has experienced since its existence and is still seeking a solution. Despite all the advances in pharmacology and technology in recent years, surgical pain remains a serious problem. This study was carried out to determine the analgesic use status and related factors according to the patients' pain levels after surgery. The study consisted of 188 patients hospitalized for surgical intervention in a private hospital operating in the province of Istanbul between 01.01.2019 and 31.12.2019 and followed up on analgesic use in the clinic for 3 days after the surgical intervention. Surgical pain averages of the patients who underwent surgery were compared according to the patient’s descriptive characteristics regarding the day of the surgery. According to this comparison, it was found that the type of surgical intervention and the character of the pain affects the incidence of pain score on the first day of surgery. It was determined that on the 1st day ...
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Introduction: Postoperative pain control plays a pivotal role in reducing postoperative complications, hospitality time, and increasing satisfaction. This study aimed to evaluate the effect of paracetamol on the pain and complications caused by gastrectomy. Materials and Methods: This randomized prospective study was conducted on 60 patients (two same group) who were candidate for gastrectomy in Imam Reza Hospital of Mashhad, Iran during August-September 2015. The first group received Patient-Controlled Analgesia (PCA) with morphine only, and in the second group, paracetamol (1 gram) infused with morphine every six hours. Level of pain, morphine intake, and side effects were evaluated in both groups. Results:No significant difference was observed in the four-scale score of pain in the patients (morphine group: 0.64±0.1, morphine-paracetamol group: 0.6±0.1) (P=0.72). During the first 24 hours after the surgery, the morphine group had lower consciousness level (2.3±0.2) compared to th...
Study of Paracetamol Infusion as Pre-Emptive Analgesic in Lower Abdominal Surgeries
IOSR Journal of Dental and Medical Sciences, 2017
Introduction: Pre-emptive analgesia is widely used to control intraoperative and postoperative pain. Intravenous Paracetamol, a non opioid analgesic gained wide popularity as to control pain during surgery. Present study is undertaken to check whether intravenous Paracetamol can be used as pre-emptive analgesic in patients undergoing lower abdominal surgeries under general anaesthesia. Methodology: 60 patients of ASA grade I & II undergoing lower abdominal surgeries under general anaesthesia were included in the study. Patients in the study group (n=30) received Paracetamol infusion (1000mg./100ml.) 15 minutes prior to induction of anaesthesia. All patients received uniform type of general anaesthesia and intra-operative fentanyl 2 mcg./kg. Monitoring includes Heart Rate (HR), Oxygen Saturation(SPO2), Blood Pressure. In the post operative period, pain is assessed at an interval of every 30 minutes till the first rescue analgesic. Pain is assessed using Visual Analogue Scale (VAS). The end point of the study is when rescue analgesic is administered to the patient. Result: Post operatively mean VAS score was better in the Paracetamol group compared to control group. Time requirement of first dose of rescue analgesic in the postoperative period was significantly prolonged in the Paracetamol group. Conclusion: It was concluded that IV Paracetamol is beneficial as a pre-emptive analgesic in patients who undergo lower abdominal surgeries.
Pain medicine (Malden, Mass.), 2016
OBJECTIVE : The management of postoperative pain is a major health care issue. While the cost of intravenous acetaminophen (IVA) is significantly greater than its oral acetaminophen (OA) counterpart, less is known regarding comparative effectiveness of these routes. The purpose of this study was to determine whether perioperative IVA is equivalent in reducing postoperative pain compared with perioperative OA for laparoscopic cholecystectomy (LapChole). Double-blinded, prospective, randomized placebo-controlled trial. Womack Army Medical Center, Fort Bragg, North Carolina. Adults (age > 18 years) active duty military, veterans, and beneficiaries receiving a laparoscopic cholecystectomy. This study was conducted at Womack Army Medical Center (WAMC), Fort Bragg, North Carolina, between January 2013 and June 2015. Sixty-seven subjects with symptomatic cholelithiasis were randomly assigned to receive two doses (1,000 mg each) of either IVA or OA. A numerical rating scale (NRS) sco...
Current concepts and practice in postoperative pain management: need for a change?
Eur Surg Res. 1999;31(2):97-107., 1999
Despite a growing trend in acute pain management, many deficiencies still account for the high incidence of moderate to severe postoperative pain to date. Patients nowadays continue to receive inadequate doses of analgesics, but additionally the identification and treatment of those patients with pain still remains a significant health care problem. Advanced techniques are available including epidural or intrathecal administration of local anaesthetics and opioids, various opioid administration techniques such as patient-controlled analgesia and infusions via sublingual, oral-transmucosal, nasal, intra-articular and rectal routes. Nonopioid analgesics such as nonsteroidal anti-inflammatory drugs and newer nonopioid drugs such as alpha2-adrenergic agonists, calcium channel antagonists and various combinations of the above are possible. However, the solution to the problem of inadequate pain relief lies not so much in the development of new drugs and new techniques, but in the effective strategy of delivering these to patients through the introduction of acute pain management services on surgical wards.
Clinical Aspects of Acute Post-Operative Pain Management & Its Assessment
Journal of Advanced …
Management of postoperative pain relieve suffering and leads to earlier mobilization, shortened hospital stay, reduced hospital costs, and increased patient satisfaction. An effective postoperative management is not a standardized regime rather is tailored to the needs of the individual patient, taking into account medical, psychological, and physical condition; age; level of fear or anxiety; surgical procedure; personal preference; and response to therapeutic agents given. The major goal in the management of postoperative pain is to minimize the dose of medications to lessen side effects & provide adequate analgesia. Postoperative pain is still under managed due to obstacles in implementation of Acute Pain Services due to insufficient education, fear of complications associated with available analgesic drugs, poor pain assessment and inadequate staff. This review reflects the clinical aspects of postoperative pain & its assessment & management with an emphasis on research for new analgesic molecules & delivery system.
Internet Journal of Pain, Symptom Control and Palliative Care
Purpose: Several studies have shown that patients often receive inadequate treatment for postoperative pain. However, there is little literature focusing on the transition process from patient-controlled intravenous analgesia (IV-PCA) and systematic (regular or as needed [PRN]) analgesia in the postoperative context. The purpose of this descriptive study is to describe the types of medication received by postoperative patients during the transition between IV-PCA and PRN analgesia, and to describe the pain assessments performed by nurses during this transition (n=36). Method: A retrospective analysis of participants' patient records by checking their medical history, analgesics prescribed and administered, and nurses' pain assessments.Results: When IV-PCA was discontinued, 52.8% of participants had no documented pain assessment and 75.0% received no PRN medication. Only 5 participants (24.8%) received analgesia. A double-entry table of the data indicates no significant relat...
International Journal of Reproduction, Contraception, Obstetrics and Gynecology
BBackground: A postoperative patient suffers from pain the best relief of which is a clinician’s duty. Till date very few studies have been conducted for comparison of paracetamol and diclofenac as analgesics. As a result a comparative study between Paracetamol and Diclofenac was carried out. The aim of the study was to compare the efficacy and side effects of intravenous Paracetamol and intravenous Diclofenac in patients undergoing major abdominal open surgeries in obstetrics and gynaecology. The study was conducted to assess the postoperative visual analogue pain scores (VAS) and total analgesic requirement in the first 24 hours and also to study the total requirement of additional analgesics despite administration of either Paracetamol or Diclofenac in postoperative period.Methods: 100 patients satisfying the inclusion/exclusion criteria were recruited for the study. They were divided into two groups of 50 each. Group A was given IV Paracetamol 6 hourly for 48 hours starting 2 ho...