Identification of stabilized dynorphin derivatives for suppressing tolerance in morphine-dependent rats (original) (raw)
Stabilized dynorphin derivatives for modulating antinociceptive activity in morphine tolerant rats: Effect of different routes of administration
Guenther Hochhaus
The AAPS Journal, 2004
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Dynorphin-(1–13): Effects in nontolerant and morphine-dependent rhesus monkeys
Mario D Aceto
European Journal of Pharmacology, 1982
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Javier Garzón
European Journal of Pharmacology, 1983
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S. Salvadori, Piero Temussi
Bioorganic & Medicinal Chemistry, 1998
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Opioid peptide dynorphin-(1–13): Adsorptive losses and potency estimates
Yao-kuang HO
Neuropeptides, 1980
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Simon Lemaire
European Journal of Pharmacology, 1991
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The degradation of dynorphin A in brain tissue in vivo and in vitro
Huda Akil
Peptides, 1987
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Central non-opioid physiological and pathophysiological effects of dynorphin A and related peptides
Simon Lemaire
Journal of psychiatry & neuroscience : JPN, 1992
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The effect of a paracetamol and morphine combination on dynorphin A levels in the rat brain
Sanzio Candeletti, Patrizia Romualdi
Biochemical Pharmacology, 2001
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A novel soluble protein factor with non-opioid dynorphin A-binding activity
Tatjana Yakovleva
Biochemical and Biophysical Research Communications, 2004
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‘Dynorphin’ in plasma: enzymatic artifact and authentic immunoreactivity
Michael Besser
Regulatory Peptides, 1984
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Design of potent and selective dynorphin A related peptides devoid of supraspinal motor effects in mice
Dr Vivek Shukla
Canadian Journal of Physiology and Pharmacology, 1993
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The effect of a paracetamol and morphine combination on dynorphin A levels in the rat brain44Abbreviations: NSAIDs, non-steroidal anti-inflammatory drugs; DYN, dynorphin; PARA, paracetamol; and ir-DYN, immunoreactive dynorphin
Patrizia Romualdi
Biochemical Pharmacology, 2001
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Development of Centrally Acting Peptide Analogs: Structure-Transport Studies and Pharmacological Evaluation of Analogs of the Opioid Peptide Dynorphin A
Amanda Carey
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Design of potent dynorphin A-(19) analogues devoid of supraspinal motor effects in mice
Robert Michelot
Canadian Journal of Physiology and Pharmacology, 1997
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[3H] dynorphin binding to guinea pig and rat brain
Huda Akil
Life Sciences, 1983
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Dynorphin B-29: Chemical synthesis and pharmacological properties in opioid systems
Patricia Sanchez-Blazquez
Neuropeptides, 1984
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Synthesis and Opioid Activity of Conformationally Constrained Dynorphin A Analogs. 1. Conformational Constraint in the "Message" Sequence
Jane Ishmael
Journal of Medicinal Chemistry, 1995
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Structure–activity relationship studies of dynorphin A and related peptides
w haq
Peptides, 1998
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Brain dynorphin and enkephalin systems in Fischer and Lewis rats: effects of morphine tolerance and withdrawal
I. Nylander
Brain Research, 1995
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A direct chemical interaction between dynorphin and excitatory amino acids
Amina Woods
Neurochemical research, 2001
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[2‘,6‘-Dimethyltyrosine]Dynorphin A(1−11)NH 2 Analogues Lacking an N-Terminal Amino Group: Potent and Selective κ Opioid Antagonists
Peter Schiller
Journal of Medicinal Chemistry, 2001
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Possible regulatory role of dynorphin-(1–13) on narcotic-induced changes in naloxone efficacy
Cankat Tulunay
European Journal of Pharmacology, 1981
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The effect of U-50,488H tolerance-dependence and abstinence on the levels of dynorphin (1–13) in brain regions, spinal cord, pituitary gland and peripheral tissues of the rat
Anil Rattan
Brain Research, 1993
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Design and synthesis of highly potent and selective cyclic dynorphin A analogs. 2. New analogs
Victor Hruby is to
Journal of Medicinal Chemistry, 1993
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Inhibition of dynorphin-converting enzymes prolongs the antinociceptive effect of intrathecally administered dynorphin in the mouse formalin test
Jerzy Silberring
European Journal of Pharmacology, 1996
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Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A(2-17) following spinal and supraspinal routes of administration
Loan Lê
Pharmacology Biochemistry and Behavior, 2009
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Dynorphin peptides differentially regulate the human κ opioid receptor
Lee-Yuan Liu-Chen
Life Sciences, 2007
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[3H]dynorphin a binding and κ selectivity of prodynorphin peptides in rat, guinea-pig and monkey brain
Huda Akil
European Journal of Pharmacology, 1986
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