Role of uric acid in hypertension, renal disease, and metabolic syndrome (original) (raw)

Hyperuricemia is increasingly recognized as a significant risk factor for cardiovascular disease, renal disease, and metabolic syndrome, contrary to historical perspectives which deemed it secondary or benign. Recent evidence indicates that elevated uric acid levels, influenced by dietary factors such as fructose intake, may contribute to the rising prevalence of obesity and diabetes. This article advocates for a reassessment of uric acid’s role in these diseases and calls for further research to explore its implications for cardiovascular health.