Clinical and imaging features of rhabdoid tumor of the kidney (original) (raw)

Aggressive uncommon pediatric renal tumor: Rhabdoid tumor of kidney

Indian Journal of Pathology and Oncology

Rhabdoid tumor of kidney is one of the uncommon pediatric renal neoplasms with highly aggressive clinical course. We are presenting a case of 1 year child with abdominal distension and hematuria. On Contrast enhanced computed tomography (CECT) a heterogenous mass in lower pole of kidney was detected. Histopathological and immunohistochemical study after radical nephrectomy revealed Malignant rhabdoid tumor of kidney. It has a tendency to metastasize early and it is associated with synchronous presence of other malignancies. No definite effective treatment for this tumor is available till now. This further necessitates the early diagnosis and prompt management which can be life saving for the patient. We are presenting this case to emphasize on its rarity and aggressive clinical behaviour.

Radiology–Pathology Conference: rhabdoid tumor of the kidney

Clinical Imaging, 2006

Rhabdoid tumor of the kidney (RTK) is a rare pediatric malignancy. Its imaging features by ultrasound and CT have been well described; however, to our knowledge, there are only a handful of case reports that describe the MR appearance of rhabdoid tumor. We report the MR appearance of a RTK in an 18-month-old boy, review the literature on its imaging features, and discuss the differential diagnosis of solid renal tumors in children. D

Rhabdoid tumors of the kidney in children: CT findings

American Journal of Roentgenology, 1995

The purpose of this study was to identify CT characteristics of rhabdoid tumor of the kidney, a rare, aggressive, malignant neoplasm of unknown origin that occurs mainly in infants and young children. MATERIALS AND METHODS. CT scans of eight children (newborn to 1 3 years old; mode, 4 months old; six boys and two girls) wIth histopathologic diagnosis of rhabdoid tumor of the kidney were evaluated retrospectively by two of the authors, who were not blinded to the diagnosis. All eight CT scans were performed with Intravenous and oral contrast, and noncontrast intravenous CT scans were available in four cases. The following CT characteristics were evaluated: location of tumor within the kidney; presence of calcification, subcapsular hematoma, multiple tumor lobules, enlarged vessels, vascular invasion, or central tumor necrosis or hemorrhage; visibilIty of tumor margin; distant metastasis; and primary tumor size.

Malignant rhabdoid tumour of kidney - a rare aggressive tumour

Journal of Clinical and Scientific Research, 2016

Malignant rhabdoid tumour of kidney is a rare highly aggressive neoplasm of childhood. We present the case of a 18- months old girl presenting with decreased appetite, abdominal distention of 20 days duration and 3 episodes of haematuria. The patient underwent left radical nephrectomy and histopathological examination of the excised specimen confirmed the diagnosis of malignant rhabdoid tumour of the kidney. This case highlights the need to consider malignant rhabdoid tumour of the kidney of possibility young children in presenting with a renal mass.

Originally misdiagnosed rhabdoid tumour of the kidney. A case report and differential diagnosis

Polish journal of pathology : official journal of the Polish Society of Pathologists, 2011

Rhabdoid tumour of the kidney (RTK) is considered to be one of the most aggressive neoplasms of early life. The histogenesis of RTK still remains a matter of controversy. Immunohistochemistry usually shows diffuse reactivity for vimentin, focal reactivity to the epithelial marker, variable expression of mesenchymal and neuroectodermal markers, and loss of INI1 protein staining. Expression of the Wilms' tumour protein (WT1) was described in the RTK cases. We would like to present a case of rhabdoid tumour of the kidney in Latvia, which caused diagnostic difficulties of a 27-month-old girl, and a short review of literature.

Rhabdoid Tumor of the Kidney: A New Case of Prenatal Diagnosis with Metastases Immediately

Medical & Surgical Urology, 2016

Rhabdoid tumor of the kidney is a rare pediatric malignancy arising most of the time before the age of two years. The diagnosis is generally difficult. The treatment is not well codified and the forecast remains very dark in spite of the progress of the pediatric oncology. We report a new case of rhabdoid renal tumor diagnosed prenatally and we specify our diagnostic and therapeutic approach.

Malignant rhabdoid tumor of the brain and kidney in a child: clinical and pathologic features

Pediatric neurology, 1995

Malignant rhabdoid tumor (MRT) is most frequently found in the kidney, but can occur in other tissues including the brain. The simultaneous appearance of MRT in the brain and kidney has rarely been described. We report the first fully described case of simultaneous appearance of MRT in the kidney and cerebellum of an 8-month-old boy. Cytoplasmic inclusion-like masses, representing aggregates of intermediate filaments, positively stained by Vimentin and by epithelial membrane antigen, were abundant in the kidney tumor but rare in the cerebellar tumor, suggesting that this often-described characteristic of kidney MRT can be an infrequently observed feature of brain MRT, which consequently may be thought to represent another type of tumor.

Rhabdoid tumor of the kidney associated with a tumor of the posterior fossa

European Radiology, 1998

We report a case of a malignant rhabdoid tumor of the kidney (MRTK) associated with a cerebellar tumor. Diagnosis was confirmed before neoadjuvant chemotherapy by a percutaneous fine-needle biopsy of the abdominal tumor. The clinical and radiologic features of this rare association of childhood neoplasms are reviewed.

The role of imaging in renal and extra-renal rhabdoid tumours

Australasian Radiology, 1996

Rhabdoid tumour of the kidney is an uncommon malignancy with a poor prognosis that usually occurs in childhood. Certain imaging features may help distinguish this lesion from the much more common Wilms' tumour. Extra-renal rhabdoid tumours appear t o have no specific imaging characteristics.

RHABDOID TUMOR OF THE KIDNEY PRESENTING WITH HEMIPLEGIA: Report of a Case

Pediatric Hematology-Oncology, 2007

Rhabdoid tumor of the kidney (RTK) is a rare and highly malignant neoplasm of infancy, with a strong tendency for early metastasis to distant regions. RTK is unique in its significant association with primary or metastatic brain tumors. The authors report the first case of RTK presenting initially with hemiplegia. The patient was found thereafter to have RTK concurrent with pulmonary metastases, a brain tumor, and a cerebral ischemic lesion. Intensive chemotherapy consisting of carboplatin and etoposide alternating with cyclophosphamide was unsuccessful and the patient died 5 months later because of severe respiratory distress resulting from widespread pulmonary metastases.