Abstract P4-20-01: Implications of financial modeling in breast cancer clinical research from 1990 to 2010 (original) (raw)

2017

Abstract

SUMMARY : Over the past two decades significant progress has been made in breast cancer treatment resulting in a substantial improvement in patients9 outcome. But we have to think about who promotes all this research and the consequences of the type of fundingThis project aims to evaluate the implication of finance in clinical research and the variance according to the type of funding. OBJETIVES : To evaluate the financial evolvement of breast cancer clinical trials in the past two decades, regarding the phase of development design of the studies, the collaboration between Academy (Acad) and Industry (Ind), the sample size, the study results and the statistical analyses conducted. METHODS: A systematic review was performed using MEDLINE to identify breast cancer randomized clinical trials published between January1990 and December2010. Studies that involved chemotherapy, endocrine and/or targeted therapies, wherethe primary endpoint was considered adequate to support a drug approval...

Miriam Lobo hasn't uploaded this paper.

Let Miriam know you want this paper to be uploaded.

Ask for this paper to be uploaded.