VDAC1 as a player in mitochondria-mediated apoptosis and target for modulating apoptosis (original) (raw)

Dominant-negative VDAC1 mutants reveal oligomeric VDAC1 to be the active unit in mitochondria-mediated apoptosis

Varda Shoshan-barmatz

Biochemical Journal, 2010

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VDAC, a multi-functional mitochondrial protein regulating cell life and death

nir arbel, Varda Shoshan-barmatz

Molecular Aspects of Medicine, 2010

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The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins

nir arbel, Adrian Israelson, Varda Shoshan-barmatz

Journal of Cell Science, 2009

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VDAC1 at the Intersection of Cell Metabolism, Apoptosis, and Diseases

ankit verma

Biomolecules, 2020

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VDAC, a multi-functional mitochondrial protein as a pharmacological target

claudie bosc

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The Mitochondrial Voltage-Dependent Anion Channel 1, Ca2+ Transport, Apoptosis, and Their Regulation

Varda Shoshan-barmatz

Frontiers in Oncology, 2017

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Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

Robert Kaiser

Nature Cell Biology, 2007

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VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria

Diego De Stefani

Cell death and differentiation, 2012

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The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis

Varda Shoshan-barmatz

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013

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Mitochondrial VDAC1: Function in Cell Life and Death and a Target for Cancer Therapy

Moran Golan, Current Medicinal Chemistry, Varda Shoshan-barmatz

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VDAC Regulation: A Mitochondrial Target to Stop Cell Proliferation

Eduardo N Maldonado

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Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect Against Mitochondria Dysfunction

Varda Shoshan-barmatz

The Journal of biological chemistry, 2016

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VDAC1 at the crossroads of cell metabolism, apoptosis and cell stress

Yakov Krelin

Cell Stress

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At the Crossroads Between Mitochondrial Metabolite Transport and Apoptosis: VDAC1 as an Emerging Cancer Drug Target

Varda Shoshan-barmatz

Stress Response Pathways in Cancer, 2014

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VDAC regulates AAC-mediated apoptosis and cytochrome c release in yeast

Manuela Côrte-Real

Microbial Cell, 2016

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Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria

Adrian Israelson

Biochemical …, 2005

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VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis

Yulia Shandalov, Moshe Gavish

Journal of Bioenergetics and Biomembranes, 2008

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Voltage-dependent anion-selective channel 1 (VDAC1)—a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane

A. Messina, Alfons Lawen

International Journal of Biochemistry & Cell Biology, 2005

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Key regions of VDAC1 functioning in apoptosis induction and regulation by hexokinase

Miri Zakar

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2009

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VDAC1 functions in Ca(2+) homeostasis and cell life and death in health and disease

Varda Shoshan-barmatz

Cell calcium, 2017

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Assembly of the Mitochondrial Apoptosis-induced Channel, MAC

Carmen Mannella

Journal of Biological Chemistry, 2009

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VDAC blockage by phosphorothioate oligonucleotides and its implication in apoptosis

Wenzhi Tan

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2012

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An N-terminal nucleotide-binding site in VDAC1: Involvement in regulating mitochondrial function

Varda Shoshan-barmatz

Journal of Cellular Physiology, 2007

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Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide

Quan Chen

Oncogene, 2004

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The Role of the Mitochondrial Apoptosis Induced Channel MAC in Cytochrome c Release

Elizabeth Jonas, Laurent Dejean, Kathleen Kinnally

Journal of Bioenergetics and Biomembranes, 2005

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The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage‐dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca 2+ signals to mitochondria

Giovanni Monaco, Patrizia Agostinis

Journal of Biological Chemistry, 2015

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The function of complexes between the outer mitochondrial membrane pore (VDAC) and the adenine nucleotide translocase in regulation of energy metabolism and apoptosis

Mikhail Vyssokikh

Acta biochimica Polonica, 2003

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Closure of VDAC causes oxidative stress and accelerates the Ca 2+-induced mitochondrial permeability transition in rat liver mitochondria

Nick Markevich

Archives of Biochemistry and Biophysics, 2010

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization

Ella Bossy-wetzel, D. Newmeyer

The EMBO Journal, 1998

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