Use of Antibiotic and Analgesic Drugs during Lactation (original) (raw)
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Considerations of drug administration during breastfeeding
Romanian Journal of Medical Practice
Breastmilk is the best nutrition for infants. Unfortunately, almost all breastfeeding mothers require medication at some point during the breastfeeding period, which sometimes leads to the cessation of breastfeeding because of false beliefs about the true risk for the infant. Many prospects drugs information about side effects avoid any administration during pregnancy or in the postpartum period; also, because of fear, mothers choose to stop breastfeeding out, and general practitioners or pediatrist calculate lower doses to administrate. In this article, we want to draw attention to that even though there are no trials in neonates; we have much data on the safe use of medication during breastfeeding. In conclusion, we want to increase awareness about the necessity of increasing knowledge for mothers and healthcare personnel about indications, contraindications, and side effects of most used medication during breastfeeding.
Characteristics of medication use during lactation
Journal of Human Growth and Development, 2018
Introdução: É inquestionável a importância do aleitamento materno. Seus benefícios abrangem o lactente, a nutriz, a família e a sociedade. A Organização Mundial de Saúde preconiza o aleitamento exclusivo até os seis meses de idade, o qual pode ser comprometido por alguns motivos, dentre eles o uso de medicamentos. Objetivo: Caracterizar os medicamentos utilizados por nutrizes, no que se refere a: categorias de risco; locais e responsáveis pela prescrição médica e orientações recebidas. Método: estudo transversal, retrospectivo, quantitativo. Os dados foram coletados na Estratégia de Saúde da Família (ESF) com 161 nutrizes nos anos de 2012 e 2013, por meio de questionário estruturado, contendo informações sobre o uso de medicamentos durante a lactação. Os dados foram apresentados em frequências absolutas e relativas, e comparados às variáveis selecionadas no estudo para verificação da existência de associação, utilizando-se o Teste do Qui-quadrado. Resultados: 55,9% das entrevistadas...
2022
Lack of information about medication intake, transfer and safety is a major risk to breastfeeding continuity. The fear of using drugs during lactation, especially newer ones, opts physicians to discontinue breastfeeding. A knowledge of the principles of drug passage into human breastmilk (HBM) can guide lactation consultants to mediate the consultations between the mother and her treating physician. Scientists have previously used preclinical rodent models for the determination of drug excretion into milk, but these are very unreliable because of marked differences in milk composition and transporters compared to those of humans. Measurement of the drug levels in humans remains the gold standard. Experimental testing in animals and computer modeling using high exposure cutoffs can also be used to predict safety.
Medications and breast-feeding: Current concepts
Journal of the American Pharmacists Association, 2012
Objectives: To describe the various factors that come into play when a breastfeeding mother is taking medications, including use of prescription drugs, over-thecounter medications, recreational drugs, galactogogues, and herbal remedies and to provide a framework used for counseling breast-feeding women. Setting: Community and hospital pharmacy and health care settings. Practice description: Consultative services provided to breast-feeding mothers who had been prescribed or were using medications. Main outcome measures: Use of pharmacokinetic factors, maternal and child factors, a list of questions to ask breast-feeding mothers, and a stepwise approach to counsel breast-feeding mothers on the compatibility of using medications while breast-feeding. Results: By positive intervention of pharmacists and health care providers, up to 1 million breast-feeding mothers, who must use medications, can continue to breastfeed while taking medications. Conclusion: Objectively weighing the benefits of drugs and breast-feeding versus the risks of drugs and not breast-feeding, in most cases, allows for pharmacists to give current and practical advice to mothers and other health professionals who counsel mothers.
Extent of Medication Use in Breastfeeding Women
Breastfeeding Medicine, 2007
The types of and extent to which medications are used by breastfeeding women have not been thoroughly investigated in the United States. The relationship between medication use during pregnancy and lactation has also been insufficiently investigated.
Clinical Research and Regulatory Affairs, 1999
The infant may be recognized as the unintended recipient of drugs administered to the lactating mother. Our objective is to create a practical classification and to provide health care practitioners with the most updated data on drug use during lactation. Data on more than one thousand drugs have been collected from published medical literature. Data include drug excretion into breast milk, possible adverse effects on the infant, as well as the compatibility of the drug with breast-feeding. Each drug is represented by two letters and symbols to identify the aforementioned information. The first letter indicates compatibility with breast-feeding, which is denoted by C (Compatible), I (Incompatible), or U (Unknown). The second letter indicates Clinical Research and Regulatory Affairs Downloaded from informahealthcare.com by South College on 02/27/13
PubMed, 2019
It is important for healthcare professionals and pregnant women to have knowledge of the risks of using medicines during pregnancy and lactation. This not only concerns the influence of the medicinal product on the pregnant woman and the pregnancy, but also its impact on the growth and development of the (unborn) child, neonatal adaptation, possible precautions regarding child-birth, drug excretion in breast milk, and the short-term and long-term consequences for the newborn child. At present, information and advices are often fragmentary, sometimes contradictory, not easily accessible, or even not available at all. It is high time for one independent source to provide unambiguous, scientifically substantiated information and advice, accessible to both healthcare professionals and pregnant women - preferably in a digital format.
Analgesics and Breast-Feeding Safety Considerations
2000
The issue of prescription of analgesics during lactation is clinically important but also complex. Most of the information available is based on single dose or short term studies, and for many drugs only a single or a few case reports have been published. As great methodological problems exist in the assessment of possible adverse drug reactions in neonates and infants,
Lactation Safety Recommendations and Reliability Compared in 10 Medication Resources
Annals of Pharmacotherapy, 2007
Background: Discontinuation of breast-feeding is linked with an increased risk of acute and chronic diseases in children, as well as increased risk of maternal disease. Mothers and physicians often depend on pharmacists for accurate drug information. Their information is only as good as the sources available to them. Objective: To determine the reliability of safety recommendations for drugs used during lactation, based on current research and information, and determine whether resources may be inappropriately advising the interruption of breastfeeding. Methods: A comparison of 10 frequently used sources for information on medication used during breast-feeding was done for 14 commonly used drugs. Our sources included the databases used by 2 retail pharmacy chains, available text references, and electronic references. We assessed the number of drugs thought to be safe in breast-feeding for each source. The drugs reviewed included those widely accepted as safe, widely regarded as not ...