Diclectin Therapy for Nausea and Vomiting of (original) (raw)

2003

Abstract

Objectives: (I) To quantify rates of suboptimal use of pyridoxine hydrochloride-doxylamine (Diclectin); and (2) to study responses to optimal doses of Diclectin in women previously taking a suboptimal dose. Methods: Women who called the Motherisk NVP helpline, and were taking only Diclectin (vitamin B6 10 mg and doxylamine I0 mg), were enrolled in the study and assessed for the severity of nausea and vomiting of pregnancy (NVP) with the Motherisk-PUQE (pregnancy-unique quantification of emesis and nausea) scoring system.Their Diclectin doses were subsequently increased according to body weight and individual symptoms. A follow-up phone call occurred within I to 3 weeks after the intervention, at which time the overall PUQE score was repeated, along with individual scoring of symptoms of nausea, vomiting, and retching. Results: Sixty-eight women were enrolled and completed the study. Despite moderate to severe NVP, defined by the validated PUQE scoring system, most women (50168) were...

Jacob Wolpin hasn't uploaded this paper.

Let Jacob know you want this paper to be uploaded.

Ask for this paper to be uploaded.