EP2 Receptor Signaling Regulates Microglia Death (original) (raw)
Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis
Luisa Minghetti
Journal of Neurochemistry, 2003
View PDFchevron_right
EP2 Receptor Signaling Pathways Regulate Classical Activation of Microglia
R. Dingledine
Journal of Biological Chemistry, 2013
View PDFchevron_right
Signal transduction pathways regulating cyclooxygenase-2 in lipopolysaccharide-activated primary rat microglia
Ravi Akundi, Peter Gebicke-haerter
Glia, 2005
View PDFchevron_right
15-Deoxy-Δ12,14-prostaglandin J2 regulates the functional state and the survival of microglial cells through multiple molecular mechanisms
Luisa Minghetti
Journal of Neurochemistry, 2003
View PDFchevron_right
Novel Microglia Cell Line Expressing the Human EP2 Receptor
Raymond Dingledine
ACS Chemical Neuroscience, 2019
View PDFchevron_right
Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: Roles in the outcome of excitotoxic brain injury
Eduardo Gallo
PLoS ONE, 2011
View PDFchevron_right
Induction of COX-2 Enzyme and Down-regulation of COX-1 Expression by Lipopolysaccharide (LPS) Control Prostaglandin E2 Production in Astrocytes
Anna Planas
Journal of Biological Chemistry, 2012
View PDFchevron_right
Expression and Regulation of Cyclooxygenase-2 in Rat Microglia
Peter Gebicke-haerter
European Journal of Biochemistry, 1997
View PDFchevron_right
Down-regulation of microglial cyclo-oxygenase-2 and inducible nitric oxide synthase expression by lipocortin 1
Lucas Parente
British Journal of Pharmacology, 1999
View PDFchevron_right
Anti-inflammatory Role of Microsomal Prostaglandin E Synthase-1 in a Model of Neuroinflammation
K. Scholich
Journal of Biological Chemistry, 2011
View PDFchevron_right
Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling
Prachi Priyam
Journal of Neuroscience, 2014
View PDFchevron_right
Molecular consequences of activated microglia in the brain: overactivation induces apoptosis
Hui Gao
Journal of Neurochemistry, 2001
View PDFchevron_right
Interactive role of the toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation
Guorong Li
Glia, 2005
View PDFchevron_right
Prostaglandin EP1 Receptor Contributes to Excitotoxicity and Focal Ischemic Brain Damage
Muzamil Ahmad, Sylvain Dore
Toxicological Sciences, 2005
View PDFchevron_right
Potential chemoprevention of LPS-stimulated nitric oxide and prostaglandin E2 production by α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranosyl-3-indolecarbonate in BV2 microglial cells through suppression of the ROS/PI3K/Akt/NF-κB pathway
kyoungtae lee
Neurochemistry International, 2014
View PDFchevron_right
Transcriptional regulation of iNOS and COX2 by a novel compound from Curcuma comosa in lipopolysaccharide-induced microglial activation
Yamaratee Jaisin
Neuroscience Letters, 2009
View PDFchevron_right
Neuroprotective erythropoietin attenuates microglial activation, including morphological changes, phagocytosis, and cytokine production
Kiyofumi Asai
Brain Research, 2017
View PDFchevron_right
Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia
Knut Biber
Journal of Neuroinflammation, 2012
View PDFchevron_right
Acetate Reduces PGE2 Release and Modulates Phospholipase and Cyclooxygenase Levels in Neuroglia Stimulated with Lipopolysaccharide
Thad Rosenberger
Lipids, 2013
View PDFchevron_right
Contribution Autotaxin protects microglial cells against oxidative stress
Christian D'Hellencourt
2011
View PDFchevron_right
Protease-activated receptor-1 regulates cytokine production and induces the suppressor of cytokine signaling-3 in microglia
Elena Pompili
International journal of molecular medicine, 2009
View PDFchevron_right
Autotaxin protects microglial cells against oxidative stress
Sandra Grès, Rana Awada, Christian D'Hellencourt
Free Radical Biology and Medicine, 2012
View PDFchevron_right
Anti-inflammatory effects of prostaglandin E2 in the central nervous system in response to brain injury and circulating lipopolysaccharide
Serge Rivest
Journal of Neurochemistry, 2008
View PDFchevron_right
Prostaglandin signaling suppresses beneficial microglial function in Alzheimer’s disease models
Siddhita Mhatre
Journal of Clinical Investigation, 2014
View PDFchevron_right
CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species
Julia Martínez Gómez
Journal of Neuroinflammation, 2012
View PDFchevron_right
Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2
Francesca Bosetti
Journal of Neuroinflammation, 2008
View PDFchevron_right
Microglia: Agents of the CNS Pro-Inflammatory Response
Dr. Nabil Hajji
Cells, 2020
View PDFchevron_right
Signal transduction and epigenetic mechanisms in the control of microglia activation during neuroinflammation
Marina Pizzi
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2016
View PDFchevron_right
Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation
R. Dingledine
Proceedings of the National Academy of Sciences, 2013
View PDFchevron_right
Microglia and neurodegeneration: The role of systemic inflammation
Colm Cunningham
Glia, 2012
View PDFchevron_right
Vitamin E (α-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia
Rufina Schuligoi
Biochemical Journal, 2003
View PDFchevron_right