Role of Oxidative Stress and Cytokines in Renal Ischemia Reperfusion Injury (original) (raw)
Annals of Tropical Medicine and Public Health
Ischemia reperfusion injury is the principal and the most severe cause of acute kidney injury. This is the result of a generalized or localized degeneration in the transportation of oxygen and nutrients to cells and the removal of waste products from kidney cells. Ischemia reperfusion injury is the main chance element for the development of persistent kidney disorder; this is explained in terms of renal or instantaneous system irregularity for more than 3 months. Throughout various clinical cases, kidneys are exposed to the ischemia reperfusion injury, interpreted by interruption of the kidney blood out glide by continued by successive perfusion development, such as resuscitation circulatory arrest, cardiac and vascular surgery, kidney transplantation and trauma. This article offers the literature's basic information to evaluate the most relevant details about the Oxidative stress and cytokines that act in renal ischemia reperfusion injury.
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