One year prevalence of psychotic disorders among first treatment contact patients at Butabika National Psychiatric Referral Hospital in Uganda (original) (raw)

One year prevalence of psychotic disorders among first treatment contact patients at the National Psychiatric referral and teaching hospital in Uganda

2019

Introduction: Hospital based studies for psychotic disorders are scarce in low and middle income countries. This may impact on development of intervention programs. Objective: We aimed to determine the burden of psychotic disorders among first treatment contact patients at the national psychiatric referral hospital in Uganda. Methods: A retrospective patient chart-file review was carried out in March 2019 for all patients presenting to the hospital for the first time in the previous year. Patients were categorised into those with and without psychotic disorders. We collected sociodemographic data on age, gender, occupation, level of education, ethnicity, religion and home district. We determined the one year prevalence of psychotic disorders among first treatment contact patients. Using logistic regression models, we also determined the association between psychotic disorders and various exposure variables among first treatment contact patients. Results: In 2018, 63% (95% CI: 60.2-65.1) of all first time contact patients had a psychosis related diagnosis. Among the patients with psychotic disorders, the median age was 29 years (IQR 24-36). Most of the patients were male (62.8%) and unemployed (63.1%). After adjusting for patients' residence, psychotic disorders were found to be more prevalent among the female gender [OR 1.58 (CI1.46-1.72)] and those of Pentecostal faith [OR 1.25 (CI 1.10-1.42)]. Conclusion: Among first treatment contact patients in Uganda, there is a large burden of psychotic disorders. The burden was more prevalent among females as well as people of Pentecostal faith who seemed to use their church for faith-based healing. Incidence studies are warranted to determine if this phenomenon is replicated at illness onset. .

Clinical and demographic features of treated first-episode psychotic disorders: A Zambian study

Schizophrenia Research, 2006

Background: There is a relative lack of information about the epidemiology of psychotic disorders in the developing world. The aim of this pragmatic study was to describe the correlates of first-episode psychosis in the central African nation of Zambia. Method: Selected clinical and demographic variables were collected on patients with psychotic disorders presenting for the first time at the only psychiatric hospital in Zambia (Chainama Hills College Hospital, Lusaka). Results: During the study period, 160 subjects were admitted to the hospital with the first episode of a psychotic disorder. The male to female sex ratio was 2.5:1, with the median age of first admission for both sexes being 26 years. Half of the subjects had a duration of untreated psychosis one month or less. Recent alcohol and other drug abuse was common in males (56%). Clinical evidence of HIV/AIDs was found in 9% of those admitted. Approximately one-third of the subjects had attended a traditional healer for their psychotic symptoms prior to admission. Conclusions: Understanding the profile of treated first-episode psychosis in the developing world can help optimize the development of local services. Furthermore, characterizing differences in the epidemiology of psychosis between populations may help generate factors that could influence its cause and course.

Prevalence of psychotic symptoms and their risk factors in urban Tanzania

International Journal of …, 2010

This study aimed to determine the prevalence of psychotic symptoms in urban Tanzania and their relationship with demographic, socio-economic and social factors. A random sample of 899 adults aged 15–59 was surveyed. The main outcome measure was endorsement of ...

Adult Psychotic Symptoms, Their Associated Risk Factors and Changes in Prevalence in Men and Women Over a Decade in a Poor Rural District of Kenya

International Journal of Environmental Research and Public Health, 2015

There have been no repeat surveys of psychotic symptoms in Kenya or indeed subSaharan Africa. A mental health epidemiological survey was therefore conducted in a demographic surveillance site of a Kenyan household population in 2013 to test the hypothesis that the prevalence of psychotic symptoms would be similar to that found in an earlier sample drawn from the same sample frame in 2004, using the same overall methodology and instruments. This 2013 study found that the prevalence of one or more psychotic symptoms was 13.9% with one or more symptoms and 3.8% with two or more OPEN ACCESS Int. J. Environ. Res. Public Health 2015, 12 5311 symptoms, while the 2004 study had found that the prevalence of single psychotic symptoms in rural Kenya was 8% of the adult population, but only 0.6% had two symptoms and none had three or more psychotic symptoms. This change was accounted for by a striking increase in psychotic symptoms in women (17.8% in 2013 compared with 6.9% in 2004, p < 0.001), whereas there was no significant change in men (10.6% in 2013 compared with 9.4% in 2004, p = 0.582). Potential reasons for this increase in rate of psychotic symptoms in women are explored.

EMPIRICAL STUDY OF PSYCHOTIC DISORDER PATIENTS IN NIGERIA

A study on psychotic disorder ailment was carried out in this research paper where the target population consists of all patients that has any of the following five psychotic disorders: Menial Brain Dysfunction (MBD); Schizophrenia; Vascular Dementia; Bipolar; and Insomnia. The sample consist of five hundred (500) psychotic patients that were selected from the entire number of psychotic patients in the hospital records (files) from January, 2010 to December, 2014. They were selected based on their peculiar ailments with symptoms of psychotic disorders. The main aim of this paper is to examine the possible existence of association among these psychotic disorders. The specific objectives are to: determine the demographic factors that influence the levels of each of these psychotic disorders; propose appropriate model for each psychotic disorder; and determine the level of correct classification using each of these models. We observed that there exist strong association among these psychotic disorders except for MBD and Vascular Demetria. Nearly all the demographic factors under consideration are one way or the other influence the levels of any psychotic disorder except divorce, injury, and genetic. The percentages of correct classification using each of the models proposed ranges between 70.8% and 91.2%.

Diagnostic accuracy at the first episode of psychosis in Uganda

medRxiv, 2020

Background: Correct clinical diagnosis at the first episode of psychosis may be difficult due to many non-specific symptoms. We determined the factors associated with a correct diagnosis among patients with a first episode of psychosis in Uganda. Methods: A cross-sectional study design was performed at the national psychiatric referral and teaching hospital in Uganda. Treatment naive participants aged 18 to 60 years with a diagnosis of a psychotic disorder were included. Patients with organic disorders like HIV/AIDS, syphilis and substance use disorders were excluded. The MINI International neuropsychiatric inventory was administered to confirm the clinical diagnosis. Concordance was based on the percentage agreement and kappa statistic between the admission chart diagnosis and the MINI diagnosis. Results: 178 participants with the first episode of psychosis were included in the final analysis. The agreement between the MINI diagnosis and clinician diagnosis was 0.385, (P < 0.001...

Study of Risk Factors in Patients Hospitalized for Psychotic Disorders in the Dalal Xel Mental Health Center in Fatick (Senegal)

MOJ Public Health

Introduction: Psychiatric disorders are characterized by the complexity of their psychodynamic mechanisms and the inadequacy of therapeutic means. This work aims to study the risk factors of psychotic pathologies in Dalal Xel hospital of Fatick. Materials and Methods: This is a cross-sectional, retrospective, study carried out between 02 June and 21 July 2014 in the Dalal Xel mental health center in Fatick. All patients hospitalized in this facility were included between November 2003 and April 2014 and their medical records were retrieved. Simple logistic regression was used to analyze the data. Results: Of the 7274 patient records collected, the average age was 34.3years (±20.32), men were the majority at 61.2% and 57.6% were from rural areas. Serer represented 39.6% of cases. The 34.9% were out of school. Psychotic forms were mostly represented (56.8%). The main factors related to psychosis after adjustment are age between 16 and 40years (OR=6,5 [5,0-8,5]), marriage (OR=0.7 IC=[0.6-0.8]), the death of the father (OR=1.3 IC=[1.1-1.5]), the death of the mother (OR=1.4 IC=[1.1-1.9]). Conclusion: Psychotic disorders are influenced by the socio-family experience of the individual. Marriage, orphan status and family support have been identified as risk factors in psychosis, hence the importance of involving the family in patient follow-up and in the development of mental health policies.

Quantitative exploration of factors influencing psychotic disorder ailments in Nigeria

Data in brief, 2017

In this data article, records on demographic data, family problem issues, as well as results of medical tests from five major classes of psychotic disorder namely: bipolar; vascular dementia, minimal brain dysfunction; insomnia; and schizophrenia, were collected on 500 psychotic patients carefully selected from the pool of medical records of Yaba Psychiatric Hospital, Lagos, Nigeria, for the period of 5 years, between January 2010 and December 2014, were examined. X-squared Statistic was used to examine each of psychotic disorders to identify demographic (age, gender, religion, marital status, and occupation) and family issues (loss of parent, history of such ailment in the family (family status), divorce, head injury, and heredity of such ailment (genetic) factors that influence them. A clear description on each of these psychotic disorders (bipolar; vascular dementia, minimal brain dysfunction (MBD), insomnia and Schizophrenia) was considered separately using tables and bar diagra...

Psychotic relapse and associated factors among patients attending health services in Southwest Ethiopia: a cross-sectional study

Background: Psychotic relapse leads to repeated hospitalization and negatively affects the clinical prognosis of the patients. Information on prevalence of relapse among patients with psychotic disorders in Ethiopian setting is scarce. This study aimed to assess the prevalence of relapse among patients with psychotic disorders attending services in Jimma University Specialized Hospital (JUSH). Methods: Data were collected using interviewer administered questionnaire. We used medication adherence rating scale (MARS) to assess compliance to medication and abnormal involuntary movement scale (AIMS) to detect medication side effects. Logistic regression analysis was used to identify independent predictors of psychotic relapse. All variables with P-value <0.25 in the bivariate analyses were entered into multivariate logistic regression and variables with P-value < 0.05 in the final model were declared to be significantly associated with the outcome variable.

Psychotic Symptoms in Kenya – Prevalence, Risk Factors, and Relationship with Common Mental Disorders

International Journal of Environmental Research and Public Health, 2012

There have been few epidemiological surveys to establish prevalence and associated risk factors of psychosis in Sub-Saharan Africa. This paper reports a populationbased epidemiological survey in rural Kenya of the prevalence of psychotic symptoms and their relationship with demographic, socio-economic and other risk factors. A random sample of 2% of all adults living in Maseno, Kisumu District of Nyanza province, Kenya OPEN ACCESS