The estimation of cerebral asymmetries in schizophrenia by the Cavalieri principle (original) (raw)

Neurosciences (Riyadh, Saudi Arabia), 2009

Abstract

To demonstrate hemispheric asymmetry in patients with schizophrenia using a cheap, simple stereologic method on the basis of standard CT scans of the brain. To demonstrate hemispheric asymmetry, standard CT scans of 30 schizophrenic patients (14 males, 16 females) were compared with 39 (13 male, 26 female) control subjects at Eskisehir Osmangazi University, Eskisehir, Turkey in 2005. Brain volumes were investigated by using a cheap, simple stereologic method, namely, Cavalieri. In patients with schizophrenia, we found that as age increases, right and left hemisphere volumes decrease. However, in the control group there was no relationship found between age and hemisphere volumes. In the control group, the left hemisphere was significantly bigger in males compared to females. There was a significant difference in both right and left hemisphere volumes between the control group and the schizophrenic group. In the schizophrenic group, a significant difference was observed in right hemi...

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