Effect of Fasting on Metabolic Syndrome in Type II Diabetic Patients (original) (raw)
Related papers
Kurdistan Journal of Applied Research
Background and aim The effect of Ramadan fasting (RF) among Metabolic Syndrome (MetS) patients is still argumentative. However, the majority of evidences demonstrated a beneficial effect on nearly most of metabolic criteria reduce the risk of MetS. Hypoglycemia is a significant consequence of diabetes that has been linked to an elevated the risk of cardiovascular disease (CVD) and hypertensions. However, conflicted results have been reported. Therefore, the aim of this study was to evaluate the impact of RF on Metabolic criteria among treated hypertensive and diabetic patients. Method This prospective observational study was carried out in a group of 73 female patients with MetS aged (20-45) years were evaluated week before and after Ramadan month having hypertension and diabetics of more than 2 years. All attending to Halabja Hospital and were treated with one daily medication based on doctor prescription. The sample random technic was used to calculate sample size and the computed...
Background: Fasting has certain effects on metabolic and anthropometric parameters in diabetic patients. It is, therefore, necessary for patients to receive proper education related to their physical activities, eating habits, blood glucose monitoring, and medications. The aim of this study was to investigate the effects of Ramadan fasting on metabolic and anthropometric indices in type ΙΙ diabetic patients.Methods: This prospective observational study was performed during Ramadan 2018. The study population consisted of diabetic patients who desired to fast and received information on physical activity, eating habits, blood glucose monitoring, and taking their medications before Ramadan. Fasting blood sugar (FBS), blood sugar 2-hour postprandial (BS2hpp), glycosylated hemoglobin (HbA1C), and the lipids profile were assessed before and after Ramadan month. FBS and BS2hpp were also evaluated on the fifteenth day of Ramadan. The significance level for data analysis was considered p<...
IUG Journal for Natural and Engineering Studies, 2013
Objectives: The aim of this study is to assess the effect of Ramadan fasting on anthropometric measures and some biochemical parameters among type 2 diabetes (T2D) patients in Gaza Governorate, Gaza Strip. Materials and methods: The design of the study is a case control (2:1). The study was carried out during the last Ramadan (late of July to August, 2011) in Gaza Governorate. A total of 80 patients suffering from the diabetes type 2, aged 40 to 65 years, have no history of diabetic complications or other diseases and treated with the same of oral hypoglycemic drugs (OHD), and compared with 40 healthy individuals as control. Anthropometric and biochemical analysis were carried out one week before Ramadan and one week before its end. Data (obtained through questionnaire interview) were analyzed using SPSS version 14. Results: The mean (± SD) of age of the participants was 53.21 (± 7.459) years for diabetic patients and 54.84 (± 6.798) years for controls (p>0.05). When the results were summed up and compared statistically, there was a statistically significant reduction in the mean of body weight (p=0.038 and p=0.000 respectively) and body mass index (BMI) (p=0.001 and p=0.000 respectively) at the end of Ramadan month in both groups as compared to pre-Ramadan. This study also found a statistically reduction in the mean (± SD) of serum fasting blood glucose (FBG) during Ramadan as compared to values before Ramadan in both groups (p=0.000 and p=0.000, respectively). A statistically significant increase in the mean (± SD) of serum triglycerides (TG) levels was also observed at the end of fasting among diabetic group (p-value=0.000). Among diabetic group, the mean (± SD) of HDL-C levels also showed significant reduction (P=0.000), while significant elevation in control group was observed (P=0.000) during Ramadan as compared to values before Ramadan. There was also statistically significant elevation in the mean (± SD) of serum total cholesterol (TC) (p-value=0.000 in both groups) and low density lipoprotein cholesterol (LDL-C) (p-value=0.000 in both groups) during the period of fasting as compared to the period before fasting in both groups. In addition, during the two periods, there were no statistical differences in the mean (± SD) of serum creatinine (p=0.0.193 and p=0.147 respectively) and urea levels (p=0.560 and p=0.143 respectively) in both groups. Concerning the glycated hemoglobin (HbA1c), the results also showed no statistical differences in the mean (± SD) of HbA1c levels (p=0.133 and p=0.905 respectively) in both groups. Conclusion: Ramadan fast is relatively safe among type 2 diabetic patients provided that they should be properly educated about drug regimen adjustment, diet control, daily activities and possible sudden complications.
Metabolic changes during Ramadan fasting in normal people and Diabetic patients
Fasting is obligatory on all Muslims every year during the 9 th Islamic lunar month of Ramadan with exemption to sick, travelers and pregnant women. In spite of the fact that Islam provides exemption from fasting to people suffering from illnesses like diabetes, many patients still want to fast for personal convictions. Physicians often face a dilemma as to how to advise them. Several studies have been published on the effects of fasting; some of the results are controversial. The present study was undertaken to establish the effects of Ramadan fasting on various physiological parameters in normal people and in diabetic patients. This could be used as basis for advice to such patients. The study group consisted of 53 diabetic patients (31 male and 22 female) and 56 (21 male 35 female) healthy volunteers as controls. Inclusion criteria of diabetic patients were: to be non-insulin dependent, and be stable and under reasonable control on oral hypoglycemic drugs and or diet control alone. The subjects were evaluated 1-2 weeks before commencement of fasting (visit 1), at the 4 th week of Ramadan fasting (visit2) and one month after the end of the Ramadan fast (visit3). Blood samples were collected on each occasion at least 8 hours after the last meal. Our results showed statistically significant weight reduction (P<.001) at the end of Ramadan fast in both groups, however it was not maintained in both groups when values were compared before Ramadan and one month after Ramadan. Fasting blood sugar and HBA1C showed significant reduction (P<.001) among diabetics but not in control group. The other parameters e.g. cholesterol, blood urea and creatinine did not show any significant changes before and during Ramadan. There was statistically significant increase in serum cholesterol and triglyceride and uric acid (P<.001) among healthy volunteers (control group) one month after Ramadan compared to before Ramadan; however no such changes were seen among diabetic group. There was no reported case of serious complication due to fasting in both groups. Conclusion: Ramadan fasting lead to significant body weight reduction and improvement of glycaemic control in diabetic patients with out other significant metabolic changes.
Romanian Journal of Diabetes Nutrition and Metabolic Diseases, 2019
Background and aims: The diabetic exempted from fasting by religion, wishing or not to observe the fast, is exposed like any other during Ramadan to a change in lifestyle. The objective of this study was to highlight the effects of Ramadan fasting on diabetes. Material and methods: Multicentre study on 899 diabetics was carried to collect data on the behaviour of diabetics with regard to the fast of Ramadan, biochemicals and anthropometry parameters. Results. The sample consists of 541 diabetic fasters (DTMF) and 358 no fasters. The causes of interruption of fasting were: hypoglycemia (82.4%), dehydration (44.5%), hyperglycemia (12.6%), high blood pressure (13.7%), loss of consciousness (8.3%). The risk factors related to fasting for DTMF were the type of diabetes and gender. Discussion and modifications about dietary, blood glucose monitoring and nutritional education sessions showed a protective effect against the occurrence of hypo and hyperglycemia and loss of consciousness. Dec...
The Effect of Fasting During Ramadan towards Improvement of Type 2 Diabetes Mellitus
2019
Original Research Article Introduction: Globally, the number of people with diabetes has been increasing trend in this modern day. Thus, this study aimed to explain the main factors of Type 2 Diabetes Mellitus (T2DM), to compare the random or fasting blood sugar before, during and after fasting month (Ramadan), and to determine the association between fasting and improvement of T2DM. Method: The total respondents of this study were 58 patients from Medical Outpatient Department. This study was used retrospective cohort study design. The data collected and recorded based on the inclusion and exclusion criteria. The fasting blood sugar for before, during and after the month of Ramadan was recorded in the designed form. The data were analysed by using SPSS version 20. Results: There were three factors of T2DM, obesity, smoking, and family history. There was no significant change of fasting blood glucose result for the comparison of three periods of time except one pair with p value of ...
Ramadan fasting is an excellent example of intermittent fasting. During Ramadan not only the food intake but the sleep pattern also alters. In spite of the exemption by the Islamic law many of the type 2 diabetic patients observe Ramadan fasting every year. The sudden change in the lifestyle which includes the change in eating and sleeping pattern can affect the various metabolic parameters in type 2 diabetic patients. The present study evaluated the anthropometric, hematological and biochemical parameters of type 2 diabetic males before and at the end of Ramadan fasting month. There was a significant reduction in the body weight, but blood pressure, total WBC count, total RBC count, hemoglobin, platelet count, fasting blood glucose, post prandial blood glucose, and HbA1c did not altered after Ramadan fasting. Total cholesterol remained unchanged while HDL increased at the end of Ramadan fasting. Triglycerides, LDL and VLDL decreased after Ramadan fasting. Renal function was affected by a significant increase in urea, creatinine and uric acid but was within physiological range. Total and direct bilirubin, total protein, albumin, globulin, ALT and AST did not altered during Ramadan fasting but there was a significant increase in the ALP. In conclusion observing Ramadan fasting does not harmfully affect type 2 diabetic patients.
The Egyptian Journal of Community Medicine, 2019
Background: During Ramadan month Muslims neither eat or drink from down to sunset. Islam exempts some Muslims from fasting including diabetic patients. However, many diabetic patients insist on fasting without proper medical advice. Objectives: To determine the clinical effects of Ramadan fasting on diabetic patients, to identify the underlying factors of these effects and to outline recommendations for safe fasting. Method: This follow up study recruited 284 Muslim diabetic patients from two hospitals in Qualubeya Governorate, of these; only 200 patients completed the study. The patients were assessed by a structured questionnaire sheet, diabetes symptom checklist, anthropometric measurement and blood samples were collected to measure fasting blood glucose, cholesterol, triglyceride, High Density Lipoprotein, Low Density Lipoprotein and glycated hemoglobin (HbA1C). Results: There was a statistically significant increase in five DM symptom domain scores at the end of Ramadan than before; neuropathic pain, psychological fatigue, cardiovascular, psychological cognitive function and hyperglycemia P<0.05 for all). Anthropometric measurements (weight, BMI, waist-hip ratio), lipid profile and HbA1C were significantly (P<0.05) decreased at the end of Ramadan. Complicated DM during Ramadan fasting was related to physical inactivity, previous DM complications during Ramadan fasting, decreased food intake, increased fluid and sugar intake. Conclusion: Ramadan fasting is associated with DM complications in diabetic patients. So, management plans are recommended to minimize these complications.
2014
Ramadan is the holy month of the Muslims where they are required to fast from dawn to sunset, with liberal access to food and fluid in the evening. The aim of this study was to measure the effect of Ramadan fasting on glucose and lipid profiles among patients with type 2 diabetes mellitus. Our study population was 58 adult diabetic patients (38females, 20males) of a mean age of 53.8±14 years. Three samples of blood were taken at three intervals (before, during and after Ramadan).the plasma glucose and lipids were measured by spectrophytometeric methods. There was an increase in the glucose level during Ramadan compared to pre Ramadan value(170 ± 44 mg/dl versus208 ± 43 mg/).after Ramadan there was a decrease of blood glucose level(165 ± 23 mg/dl).the triglyceride concentrations in pre, during and after Ramadan respectively were(152 ± 23 mg/dl, 182 ± 31 mg/dl, 162 ± 19 mg/dl). The total cholesterol concentrations in pre, during and after Ramadan respectively were (184 ± 29 mg/dl, 224...