An Uncommon Cause of Spreading Cellulitis in a Case of Acute Myeloblastic Leukemia (original) (raw)

2015

Abstract

Mucormycosis, earlier known as zygomycosis, is a rapidly fatal fungal infection especially in immunocompromised hosts. In spite of active management the mortality due to mucormycosis remain very high till today. The common genera associated with such type of infections are Absidia, Mucor, Rhizomucor and Rhizopus. Apophysomyces elegans is relatively new in this context. It was first isolated from India in 1979 (Misra P.C. et al., 1979). Also documented in southern United States, Australia, Mexico, Carribean Islands, Columbia and Venezuela. Nearly 100 cases are reported till date and majority are from India. Most important risk factor for A. elegans infection is wound contamination with soil (Sedralis T. et al., 1997). A. elegans not only causes cutaneous or mucocutaneous infection but also associated with deep seated serious infections like rhino-orbito-cerebral and renal zygomycosis.

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