Extraction of indole alkaloids from Tabernaemontana catharinensis using supercritical CO 2+ethanol: an evaluation of the process variables and the raw material origin (original) (raw)

Journal of Supercritical Fluids, 2004

Abstract

Indole alkaloids from Tabernaemontana catharinensis, collected from different places, were extracted using a mixture of supercritical CO2 plus ethanol. The effects of the process variables: temperature, pressure, solvent flow rate, and percentage of cosolvent on the total yield, chemical composition of the extract, and extraction kinetics were determined. The extracts were solvent-partitioned and their composition analyzed by TLC, GC-MS and

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