Lung Carcinoid Tumor: A Case Report (original) (raw)
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Primary typical pulmonary carcinoid tumor: an incidental finding
Comparative Clinical Pathology, 2017
Bronchopulmonary carcinoid tumors are rare tumors (only 0.5 to 2.5% of all pulmonary tumors) that arise from neuroendocrine cells known as Kulchitsky cells. They are characterized by slow growth and rarely metastasize beyond the lungs. However, they can occur in the central or peripheral parts of the lung. Secondary locations can be asymptomatic, but central carcinoids often present with obstructive signs including: recurrent pneumonias and hemoptysis. We report a rare, asymptomatic case of a primary bronchopulmonary carcinoid in a 62-year-old man. A 62year-old man presented with history of intermittent right upper quadrant pain, especially after a high fat meal, for 6 months. Systemic examination was unremarkable. Ultrasonography of gall bladder showed cholelithiasis, and he was scheduled for cholecystectomy. On preoperative cardiology consult, the chest X-ray showed an incidental homogenous opacity in the right middle zone without any respiratory symptoms. Patient underwent fiber optic bronchoscopy and biopsy. Histopathologic examination showed monomorphic tumoral cells forming small nests, rosette-like arrangements, and cords with salt and pepper, stippled appearance nuclei. Patient underwent right middle lobectomy. The postoperative period was uneventful, and the patient was disease-free in the following 25 months. Carcinoid syndrome is very rare in patients with bronchopulmonary carcinoid tumors. Overall prognosis for patients with typical bronchopulmonary carcinoid tumors is favorable. If diagnosed in the early stages, the chances for radical treatment success are increased.
Elsevier eBooks, 2018
Background: Pulmonary carcinoid tumor is a low-grade malignant neoplasm comprised of neuroendocrine cells. The aim of this study was to determine the clinical features; radiological and bronchoscopic findings, as well as treatment in patients. The hospital records of 21 patients with pulmonary carciniod tumor, who admitted to NRITLD between 1995 and 2001, were evaluated. Results: 19 patients had typical and 2 had atypical carcinoid tumor. Male to female ratio was 1.1. The mean age ± SD was 39.33±16.31.Cough (80.9%) was the most common presenting symptom. 16 patients had abnormal chest radiography. The diagnosis was made using bronchoscopy and biopsy. Most of the tumors arose in main bronchi. Surgery with or without endobronchial laser therapy was the treatment of our patients. Lobectomy (47.3%) was the most common procedure. surgery with or without laser therapy has a favorable outcome in pulmonary carcinoid tumors.
Bronchial carcinoid tumors: A rare malignant tumor
Nigerian Journal of Clinical Practice, 2015
Bronchial carcinoid tumors (BCTs) are an uncommon group of lung tumors. They commonly affect the young adults and the middle aged, the same age group affected by other more common chronic lung conditions such as pulmonary tuberculosis. Diagnosis is commonly missed or delayed due to a low index of suspicion. Surgery is the mainstay of treatment with an excellent outcome. There are many reports of this rare group of tumors in the Western and Asian regions. The only report around our sub-region is a post mortem report of an atypical variant. We wish to report a case of the typical variant and increase our index of suspicion. A 25-year-old male presented with a 4 years history of cough and haemoptysis. He was repeatedly treated for bronchial asthma and pulmonary tuberculosis with no improvement of symptoms. Chest X-ray and chest computed tomography scan revealed a left upper lobe tumor. Histology reported a typical variant of BCT which was confirmed by immunohistochemistry. He had a left upper lobectomy and has done excellently well thereafter. A high index of suspicion is needed to reduce the risk of missing or delaying the diagnosis.
Carcinoid tumors of the lung: A report of 11 cases
Asian Journal of Surgery, 2013
Objective: Carcinoid tumors of the lung are rare, and account for 1% of all primary tumors of the lung. This study was undertaken to investigate the histological characteristics and clinical behavior of carcinoid tumors of the lung. Methods: We have retrospectively reviewed the hospital records of 11 consecutive patients undergoing surgical treatment for carcinoid tumors of the lung between 1992 and 2007. Results: Patients with carcinoid tumors accounted for 0.8% (11 of 1319) of the patients undergoing surgical treatment for nonsmall cell lung cancer. The group comprised six males and five females with a mean age at presentation of 58.6 years (range 27e78 years). All of the operations were lobectomies, including two sleeve lobectomies. Six patients had typical and five had atypical carcinoid tumors. Seven patients had stage IA disease, two had stage IB, one had stage IIA, and one had stage IIIA. Recurrent tumors developed in two of the five patients affected by atypical carcinoid tumors, but none of the six patients with typical carcinoid tumors. Overall, the 5-year survival rate of patients with both typical and atypical carcinoid tumors was 90.9%. Conclusion: Survival of carcinoid tumors was favorable. In this analysis, two patients with atypical carcinoid had postoperative recurrences. Recurrence was more common among patients with atypical carcinoid tumors.
Disseminated typical bronchial carcinoid tumor
Vojnosanitetski pregled, 2013
Introduction. Bronchial carcinoids belong to a rare type of lung tumors. If they do not expose outstanding neuroendocrine activity, they develop without clearly visible symptoms. They are often detected during a routine examination. According to their clinical pathological features, they are divided into typical and atypical tumors. Typical bronchial carcinoids metastasize to distant organs very rarely. Localized forms are effectively treated by surgery. The methods of conservative treatment should be applied in other cases. Case report. We presented a 65-year-old patient with carcinoid lung tumor detected by a routine examination. Additional analysis (chest X-ray, computed tomography of the chest, ultrasound of the abdomen, skeletal scintigraphy, bronhoscopy, histopathological analysis of the bioptate of bronchial tumor, as well as bronchial brushing cytology and immunohistochemical staining performed with markers specific for neuroendocrine tumor) proved a morphologically typical ...
Pulmonary Carcinoid Tumour of Endobronchial Presentation: A Case Report
Introduction: Lung carcinoid tumors account for 1-2 % of malignant lung neoplasms. Early diagnosis is crucial, and surgery at an early stage may improve the clinical picture and may even be a curative option. Case report: We present the case of a 78-year-old woman with a history of poorly controlled arterial hypertension, anxious syndrome, irritable bowel syndrome, and paroxysmal palpitations for the last two years. Imaging showed a left hilar nodular lesion causing endobronchial obstruction in the left lower lobe. Anatomopathology revealed a low-grade pulmonary neuroendocrine tumor, and pulmonary resection with nodal staging was promptly considered. Conclusions: The diagnosis of pulmonary carcinoid tumor is challenging; therefore, it is necessary to maintain suspicion in patients with non-specific and/or persistent respiratory symptoms, and complete resection and prolonged close follow-up should be considered despite a satisfactory postoperative course.
Atypical diagnosis for typical lung carcinoid
BMC Pulmonary Medicine
Background: The diagnosis of lung typical carcinoid tumors results challenging when limited size and unfavorable sampling location is associated. It has been reported that bronchoscopy with endobronchial ultrasound (EBUS) significantly increases the diagnostic yield of peripheral nodules smaller than 2 cm. Case presentation: A 70-year-old Caucasian male complained of persistent fever and cough despite several antibiotic courses and steroid treatment. Chest radiology revealed the presence of a small single nodular opacity in the left upper lobe, whose standardized maximum uptake value (SUV) at fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) was significantly high (4.5). The patient underwent bronchial endoscopy but any appreciable sign of endobronchial or intramural involvement was detected. Only radial ultrasound-guided bronchoscopy (R-EBUS) allowed transbronchial sampling whose pathological analysis revealed a typical carcinoid tumor. The patients underwent surgical lobectomy and clinic-radiological follow was started. Conclusions: With this case we aim at stressing the importance of ultrasound in the diagnostic process of lung small peripheral carcinoid, especially if they present without mucosal or sub mucosal involvement.
Carcinoid tumor with localized bronchiectasis
Tanaffos, 2013
Bronchial carcinoid tumor comprises 1 to 3% of lung neoplasms. The common age of onset is mainly post-puberty although atypical carcinoid tumors occur at ages 44 to 55. Carcinoid tumors cause two groups of symptoms in patients: symptoms due to obstruction and symptoms due to the production and release of active neuropeptides. Histologically, carcinoid tumors are categorized into two groups of typical and atypical while in terms of location of lesion, they are grouped into central and peripheral types. Differentiation between malignant and benign carcinoid tumors is based on presence or absence of metastasis. Bronchoscopy and endobronchial biopsy are the best diagnostic measures in these patients. Serologic evaluation and assessment of active metabolites in case of liver metastasis also help the diagnosis. Surgical resection is the treatment of choice for this condition. This report discusses a patient with carcinoid tumor who was receiving bronchodilator treatment for a couple of mo...