Prodrugs capable of releasing a retinoic derived by taking advantage of the enzymatic activity of the cutaneous surface and pharmaceutical and / or cosmetic (original) (raw)

1999

Abstract

The present invention provides a ternary glucosyl complex, bioprecursor of at least one retinoic active principle, intended for percutaneous application, of formula (I) (CF DRAWING IN BOPI) wherein: - E represents a linear hydrocarbon spacer group, branched or cyclized aliphatic or aromatic character which can contain one or more heteroatom (s) and oxygen may bear one or more group (s) carbonyl, - a represents a residue of a molecule of said retinoic active principle, linked to the spacer group by a carboxylate functional group, - n = 1 or 2.

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