Aldehyde test (Formol-Gel test) in the diagnosis of kala-azar (visceral leishmaniasis) (original) (raw)

Tropical doctor, 1992

Abstract

INTRODUCTION The demonstration of Leishman-Donovan bodies (amastigotes) in spleen, bone-marrow or lymph node aspirates provides the definitive diagnosis of Kala-azar. These procedures have some limitationsI,2 because they are not always practicable in rural settings. Specific serological tests are complex, require trained manpower and a well equipped laboratory. People of low socio-economic group residing in the rural area are often the victims of Kala-azar. They are usually beyond the reach of well equipped laboratory facilities. In such circumstances the aldehyde test (AT) (Formol-Gel test), which is nonspecific, is simple to do and less costly. This communication assesses the role of this test in the diagnosis of Kala-azar in a part of the world where the diagnostic facilities are scarce.

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