The role of urodynamic studies in the diagnosis and treatment of patients with spina bifida (original) (raw)

2015, Asian Journal of Neurosurgery

sinus, tethered cord syndrome, diastomatomyelia, lumbosacral lipoma, neurenteric cyst, lipomeningomyelocele, and anterior meningocele. Before prenatal ultrasonography, SB was a pathology that could only be diagnosed at the time of birth. On the other hand, there are differences in the incidence of SD with respect to race, familial and genetic factors, and diet, as well as prominent regional differences. [1] While there is a decrease in this incidence depending on the antenatal early diagnosis and performing therapeutic abortion methods when needed, there is again an increase due to globalization and accompanying migration. [4,5] The embryo pathogenesis of SD is still unclear. The combined defects involving each three germ layers are present during the etiopathogenesis. As a result of defects that occur during neural tube development between day 20 and day 60 after ovulation, only a minor defect may be present in the posterior vertebra elements depending on its time, or they may appear as complex lesions accompanied by additional pathologies, which progress with widespread neural disorders. [6] In addition, organ anomalies may be observed in the central nervous system and/or other systems. Patients with intrauterine diagnosis who are monitored may be the patients who were diagnosed with congenital neural