Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication in vitro and provide a rationale to redesign antiretroviral treatment for feline AIDS (original) (raw)

Preclinical Evaluation of 1H-Benzylindole Derivatives as Novel Human Immunodeficiency Virus Integrase Strand Transfer Inhibitors

Laura Luca

Antimicrobial Agents and Chemotherapy, 2008

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New Class of HIV Integrase Inhibitors that Block Viral Replication in Cell Culture

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HIV1 integrase strand-transfer inhibitors: Design, synthesis and molecular modeling investigation

Laura De Luca

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A Versatile and Practical Synthesis toward the Development of Novel HIV-1 Integrase Inhibitors

Giulia Vignaroli

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New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

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Inhibitors of human immunodeficiency virus integrase

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Development of an AlphaScreen-Based HIV-1 Integrase Dimerization Assay for Discovery of Novel Allosteric Inhibitors

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Specific Inhibition of Human Immunodeficiency Virus Type 1 (HIV1) Integration in Cell Culture: Putative Inhibitors of HIV1 Integrase

Raman Kumar

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Integrase Strand Transfer Inhibitors as potential anti-HIV agent

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GERF Bulletin of Biosciences

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Development of a Human Immunodeficiency Virus Vector-Based, Single-Cycle Assay for Evaluation of Anti-Integrase Compounds

roberta Bona

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Preclinical Evaluation of GS-9160, a Novel Inhibitor of Human Immunodeficiency Virus Type 1 Integrase

Matthew Wright

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Molecular Modeling Studies and ADME Screening on HIV-1 Integrase Inhibitors as Anti-Viral Agents

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Progress in development of HIV-1 integrase inhibitor

Shikha Kaushik

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Conformational aspects of HIV-1 integrase inhibition by a peptide derived from the enzyme central domain and by antibodies raised against this peptide

Richard Maroun

European Journal of Biochemistry, 1999

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The discovery and preclinical evaluation of BMS-707035, a potent HIV-1 integrase strand transfer inhibitor

Nicholas Meanwell

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Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

Larry Miercke

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HIV-1 Integrase: From Biology to Chemotherapeutics

Erika Loizidou

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HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

Amy Espeseth

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A targeted DNA substrate mechanism for the inhibition of HIV-1 integrase by inhibitors with antiretroviral activity

Zeina Hobaika

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Mechanism of Inhibition of HIV-1 Integrase by G-tetrad-forming Oligonucleotides in Vitro

Rahul Mitra

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Selection of human immunodeficiency virus type 1 R5 variants with augmented replicative capacity and reduced sensitivity to entry inhibitors during severe immunodeficiency

Eva M Fenyƶ

Journal of General Virology, 2005

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Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration

Bruno Klaholz

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In Silico and In Vitro Comparison of HIV-1 Subtypes B and CRF02_AG Integrases Susceptibility to Integrase Strand Transfer Inhibitors

X. Ni, Safwat S A Abdel-azeim

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