The prevalence and outcome of excess body weight among Middle Eastern patients presenting with acute coronary syndrome (original) (raw)
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Annals of Saudi medicine
To describe the distribution of body mass index (BMI) and its relationship with clinical features, management, and in-hospital outcomes of patients admitted with acute coronary syndromes (ACS). The Saudi Project for Assessment of Coronary Events is a prospective registry. ACS patients admitted to 17 hospitals from December 2005-2007 were included in this study. BMI was available for 3469 patients (68.6%) admitted with ACS and categorized into 4 groups: normal weight, overweight, obese, and morbidly obese. Of patients admitted with ACS, 72% were either overweight or obese. A high prevalence of diabetes (57%), hypertension (56.6%), dyslipidemia (42%), and smoking (32.4%) was reported. Increasing BMI was significantly associated with diabetes, hypertension, and hyperlipidemia. Overweight and obese patients were significantly younger than the normal-weight group (P=.006). However, normal-weight patients were more likely to be smokers and had 3-vessel coronary artery disease, worse left ...
Reality of obesity paradox: Results of percutaneous coronary intervention in Middle Eastern patients
Journal of International Medical Research
Objective The aim of this study was to assess the baseline clinical characteristics, coronary angiographic features, and adverse cardiovascular events during hospitalization and at 1 year of follow-up in obese patients compared with overweight and normal/underweight patients. Methods A prospective, multicenter study of consecutive patients undergoing percutaneous coronary intervention was performed. Results Of 2425 enrolled patients, 699 (28.8%) were obese, 1178 (48.6%) were overweight, and 548 (22.6%) were normal/underweight. Obese patients were more likely to be female and to have a higher prevalence of diabetes, hypertension, hypercholesterolemia, or previous percutaneous coronary intervention. Acute coronary syndrome was the indication for percutaneous coronary intervention in 77.0% of obese, 76.4% of overweight, and 77.4% of normal/underweight patients. No significant differences in the prevalence of multi-vessel coronary artery disease or multi-vessel percutaneous coronary int...
Journal of Obesity, 2012
Although obesity is a well-established cardiovascular risk factor, some controversy has arisen with regard to its effect on hospital mortality in patients admitted for acute coronary syndrome.Methods. Clinical and anthropometric variables were analyzed in patients consecutively admitted for acute coronary syndrome to a university hospital between 2009 and 2010, and the correlation of those variables with hospital mortality was examined.Results. A total of 824 patients with a diagnosis of myocardial infarction or unstable angina were analyzed. Body mass index was an independent factor in hospital mortality (odds ratio 0.739 (IC 95%:0.597-0.916),P=0.006). Mortality in normal weight(n=218), overweight(n=399), and obese(n=172)subjects was 6.1%, 3.1%, and 4.1%, respectively, with no statistically significant differences between the groups.Conclusions. There is something of a paradox in the relationship between body mass index and hospital mortality in patients with acute coronary syndrom...
Abdominal obesity pattern among various ethnic groups presenting with acute coronary syndrome
Journal of Ayub Medical College, Abbottabad : JAMC
Abdominal obesity is an increasing public health problem and is associated with a number of cardiovascular risk factors. The aim of this study was to determine the frequency of abdominal obesity and associated risk factors in patients of various ethnic groups presenting with acute coronary syndrome. A total of 477 patients presenting with acute coronary syndrome to the National Institute of Cardiovascular Diseases, Karachi were studied. The sample was divided into 5 major ethnic groups, Muhajir, Punjabi, Sindhi, Pathan, Baluchi and Others. Waist circumference of each patient was taken at the level of iliac crest and abdominal obesity was defined according to the International Diabetes Federation criteria of 2005 for South Asians as waist circumference > or = 90 Cm in males and > or = 80 Cm in females. Patients were also assessed for diabetes mellitus, hypertension, smoking, low HDL and elevated triglycerides. Out of 477 patients (355 males, 122 females), abdominal obesity was ...
Journal of Clinical Hypertension, 2010
J Clin Hypertens (Greenwich).The objective of this study was to evaluate the prevalence and effect of the metabolic syndrome (MetS) on patients with acute coronary syndrome (ACS) in six Middle Eastern countries using the new definition of MetS. Analysis of the Gulf Registry of Acute Coronary Events (Gulf RACE), which included 8716 consecutive patients hospitalized with ACS, was conducted and patients were divided into two groups: patients with and patients without the MetS. Overall, 46% of patients had MetS. Patients with MetS were more likely to be female and less likely to be smokers. In-hospital mortality and cardiogenic shock were comparable between the two groups, although MetS patients were more likely to have congestive heart failure and recurrent ischemia. In ST-elevation myocardial infarction, MetS was also associated with increased risk of recurrent myocardial infarction and stroke. Using the recent MetS definition, MetS is highly prevalent among Middle Eastern patients presenting with ACS. MetS is associated with higher-risk profile characteristics and increased risk for development of heart failure and recurrent myocardial ischemia without an increase in hospital mortality. J Clin Hypertens (Greenwich). 2010;12:890–899.