A case of metastatic axillary lymph nodes involvement from unknown primary cancer: clinical usefulness of [99mTc]- sestamibi (original) (raw)

Tumori

Abstract

Metastatic cancer of unknown primary site is characterized by a poor prognosis. Nevertheless, in the case of suspected breast cancer, patients may have the same prognosis of stage II patient". Technetium-99m-hexakis-2-methoxy-isobuty1-isonitrile (sestamibi) is a lipophilic cation widely employed as a myocardial perfusion imaging agent. Latest diagnostic applications in oncology confirmed [99ffiTc]-sestamibi as an useful tracer for the visualization of a variety of primitive and secondary tumors2,4,7. 10. Nuclear medicine procedures using single photon emission tomography (SPET) are currently being assessed with the aim of improving lesion detection1. These techniques proved to have a higher specificity than planar acquisition. Moreover, new instrumentation has made it possible to acquire and reconstruct SPET images within a short time, making it a useful tool in clinical practice.

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