Expression of mutant  2 nicotinic receptors during development is crucial for epileptogenesis (original) (raw)

Expression of mutant β2 nicotinic receptors during development is crucial for epileptogenesis

Cecilia Gotti

Human Molecular Genetics, 2009

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Nicotinic Receptors in Sleep-Related Hypermotor Epilepsy: Pathophysiology and Pharmacology

Laura Clara Grandi, Giulia Colombo

Brain Sciences, 2020

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The role of nicotinic acetylcholine receptors in autosomal dominant nocturnal frontal lobe epilepsy

Alida Amadeo

Frontiers in physiology, 2015

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Genetic Variant in Nicotinic Receptor α4-Subunit Causes Sleep-Related Hyperkinetic Epilepsy via Increased Channel Opening

Steven m. M Sine

International Journal of Molecular Sciences

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Neuronal nicotinic receptors and epilepsy, from genes to possible therapeutic compounds

Ronald Hogg

Bioorganic & Medicinal Chemistry Letters, 2004

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Properties of mutated murine α4β2 nicotinic receptors linked to partial epilepsy

Eleonora Katz

Neuroscience Letters, 2008

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Increased Sensitivity of the Neuronal Nicotinic Receptor α2 Subunit Causes Familial Epilepsy with Nocturnal Wandering and Ictal Fear

Tiziana Pisano

The American Journal of Human Genetics, 2006

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Altered activity–rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor

Gustavo Dziewczapolski

Molecular Psychiatry, 2011

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Nicotine Normalizes Intracellular Subunit Stoichiometry of Nicotinic Receptors Carrying Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy

Bruce Cohen, Fraser Moss

Molecular Pharmacology, 2009

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Multi-electrode array study of neuronal cultures expressing nicotinic β2-V287L subunits, linked to autosomal dominant nocturnal frontal lobe epilepsy. An in vitro model of spontaneous epilepsy

G. Casari

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Multi-electrode array study of neuronal cultures expressing nicotinic β2-V287L subunits, linked to autosomal dominant nocturnal frontal lobe epilepsy. An in vitro model of spontaneous epilepsy

Irene Manfredi, Enzo Wanke

Frontiers in Neural Circuits, 2014

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Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function

Heidi O'Neill

Pharmacology Biochemistry and Behavior, 2013

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Potential Role of the α4 and α6 Nicotinic Receptor Subunits in Regulating Nicotine-Induced Seizures

theresa tritto, Jerry Stitzel

Journal of Pharmacology and Experimental Therapeutics, 2000

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Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy

J. Glykys

Proceedings of the National Academy of Sciences, 2006

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Increased sensitivity to agonist-induced seizures, Straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive α4 nicotinic receptors

Michael Marks

2003

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Exclusion of linkage of nine neuronal nicotinic acetylcholine receptor subunit genes expressed in brain in autosomal dominant nocturnal frontal lobe epilepsy in four unrelated families

Rosanna Asselta

Journal of Neurology, 2002

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Nicotine-Induced Dystonic Arousal Complex in a Mouse Line Harboring a Human Autosomal-Dominant Nocturnal Frontal Lobe Epilepsy Mutation

Andrew Lawrence

The Journal of Neuroscience, 2007

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Investigation of the role of nicotinic acetylcholine receptors in modulating epileptiform activity

Shiva Roshan-Milani

2004

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Mutational Analysis of Nicotinic Acetylcholine Receptor β2 Subunit Gene (CHRNB2) in a Representative Cohort of Italian Probands Affected by Autosomal Dominant Nocturnal Frontal Lobe Epilepsy

Rosanna Asselta

Epilepsia, 2002

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Human Nocturnal Frontal Lobe Epilepsy: Pharmocogenomic Profiles of Pathogenic Nicotinic Acetylcholine Receptor -Subunit Mutations outside the Ion Channel Pore

Stylianos Antonarakis

Molecular Pharmacology, 2008

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Mutation Causing Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Alters Ca2+Permeability, Conductance, and Gating of Human α4β2 Nicotinic Acetylcholine Receptors

Vladimir Gerzanich

The Journal of Neuroscience, 1997

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Increased sensitivity to nicotine-induced seizures in mice expressing the L250T α7 nicotinic acetylcholine receptor mutation

Ramiro Salas

Molecular …, 2002

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Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Affect Allosteric Ca2+ Activation of the 4 2 Nicotinic Acetylcholine Receptor

Henry Lester

Molecular Pharmacology, 2005

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Increased Sensitivity to Nicotine-Induced Seizures in Mice Expressing the L250T alpha 7 Nicotinic Acetylcholine Receptor Mutation

Ron Broide

Molecular Pharmacology, 2002

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