Attenuation of IgE Affinity for FcϵRI Radically Reduces the Allergic Response in Vitro and in Vivo (original) (raw)

Chapter 3 New Insights on Mast Cell Activation via the High Affinity Receptor for IgE

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Attenuation of IgE Affinity for Fc RI Radically Reduces the Allergic Response in Vitro and in Vivo

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IgE Enhances Mouse Mast Cell FcεRI Expression In Vitro and In Vivo: Evidence for a Novel Amplification Mechanism in IgE-dependent Reactions

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Cutting edge: death of a dogma or enforcing the artificial: monomeric IgE binding may initiate mast cell response by inducing its receptor aggregation

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Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases.

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IgE-induced passive sensitization of human isolated bronchi and lung mast cells

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Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the Fc RI

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NOVEL TREATMENT STRATEGIES AND REGULATION OF IgE-MEDIATED ALLERGIC

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IgE Influences the Number and Function of Mature Mast Cells, but Not Progenitor Recruitment in Allergic Pulmonary Inflammation

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Increased Expression of High Affinity IgE (Fc ɛ RI) Receptor- α Chain mRNA and Protein-bearing Eosinophils in Human Allergen-induced Atopic Asthma

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Non-IgE mediated mast cell activation

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Enhanced expression of high-affinity IgE receptor (FcϵRI) α chain in human allergen-induced rhinitis with co-localization to mast cells, macrophages, eosinophils, and dendritic cells

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Pivotal Advance: IgE accelerates in vitro development of mast cells and modifies their phenotype

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Toru, H. et al. Induction of the high-affinity IgE receptor (FcRI) on human mast cells by IL-4. Int. Immunol. 8, 1367-1373

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Inhibition of allergen-specific IgE reactivity by a human Ig Fcγ-Fcε bifunctional fusion protein

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Mast cells regulate IFN-[gamma] expression in the skin and circulating IgE levels in allergen-induced skin inflammation* 1

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Substance P downregulates expression of the high affinity IgE receptor (FcεRI) by human mast cells

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Multistep IgE Mast Cell Desensitization Is a Dose- and Time-Dependent Process Partially Regulated by SHIP-1

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A molecular model of type I allergy: Identification and characterization of a nonanaphylactic anti-human IgE antibody fragment that blocks the IgE-FcϵRI interaction and reacts with receptor-bound IgE

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Production of IL-5 and granulocyte-macrophage colony-stimulating factor by naive human mast cells activated by high-affinity IgE receptor ligation

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