Unusual presentation of mycosis fungoides as a lump in the scalp (original) (raw)

Mycosis fungoides with central nervous system involvement

International journal of dermatology, 2000

The Correspondence Section serves as a forum for opinion exchange about subjects of general interest such as dermatologic training, relations between dermatologists and pharmaceutical houses, governmental control of dermatology and medical practice in general, peculiarities of dermatology related to geographic, climatic, or racial factors, the¯ow of information and publications, as well as other concerns the readership might have. Contributions are welcome and should conform to the usual format for correspondence. Manuscripts will undergo standard editorial procedures. Submit all correspondence to Roberto Corte  s Franco, MD, Fax: +52 (5) 665 7691.

Mycosis Fungoides: Case Report and Literature Review

Clinical Medicine Insights: Case Reports, 2014

Mycosis fungoides (MF), also known as Alibert-Bazin syndrome or granuloma fungoides, is the most common form of cutaneous T-cell lymphoma. Cutaneous lymphomas are an uncommon, heterogeneous group of non-Hodgkin lymphomas (NHLs) of T-and B-cell origin where the skin is the primary organ of involvement. This is a case of a 60-year-old Nigerian woman, who was diagnosed and managed as a case of chronic dermatitis but further investigations confirmed a diagnosis of MF; she was thereafter managed with topical glucocorticoids/chemotherapy and improved on these treatments. We make a plea for better awareness of the disease among physicians and pathologists in Africa.

Dermoscopy in the Diagnosis of Mycosis Fungoides: Can it Help?

Dermatology Practical & Conceptual

Introduction: The diagnosis of mycosis fungoides (MF) is challenging since it can mimic a variety of benign skin conditions. Multiple biopsies for histopathologic and immunohistochemical examination are required to diagnose MF. Dermoscopy is an affordable, non-invasive device with expanding indi-cations in dermatology, Objectives: To investigate the dermoscopic morphology of MF variants and assess the correlation between dermoscopic criteria, histopathologic, and immunohistochemical findings, Methods: We included 88 patients with several MF variants (classic, hypopigmented, hyperpigment-ed, poikilodermatous, erythrodermic, and folliculotropic).The diagnosis was histopathologically and immunohistochemically confirmed. Dermoscopic findings were collected, statistically analyzed, and correlated with the results of histopathology and immunohistochemistry, Results: All patients had MF diagnosis in H&E-stained sections.The majority revealed positive stain-ing with CD3, 4, 8 and negative C...

Mycosis fungoides: The great imitator

Introduction: Mycosis fungoides although a cutaneous T-Cell lymphoma can immitate many dermatological disorders. A 60 year old man presented to our hospital with generalized annular plaques, few with verrucous surface. The annular lesions imitated Psoriasis, Tinea, Syphilis and the diagnosis was in dilemma. Histopathology gave the light and path to diagnosis. Case report: A 60 year old man presented with complains of erythematous scaly lesions since 20 year, Lesions were initially flat and erythematous which later became ulcerated, crusted and painful. H/O exacerbation and remission was present. Conclusions: Mycosis Fungoides is a great imitator both clinically and histopathologically. We are presenting a case report of patient with Mycosis Fungoides, Stage IIA.

Mycosis Fungoides and Head and Neck Malignancies

Journal of Case Reports in Medicine, 2013

Mycosis fungoides is a cutaneous T-cell lymphoma characterized by cutaneous patches and plaques that may progress to hematologic involvement and Sezary syndrome. Second primary tumors have been described in the literature without emphasis on head and neck neoplasms. We report two cases of head and neck malignancies in patients with a history of mycosis fungoides. A PubMed literature search was performed and results were reviewed. Second primary tumors in the head and neck have been reported in the nose and nasal cavity, sinuses, oral cavity, pharynx, hypopharynx, larynx, tracheobronchial tree, thymus, and skin. We present cases of submandibular mucoepidermoid carcinoma and papillary thyroid carcinoma in patients with a history of mycosis fungoides. Mycosis fungoides may confer increased risk of developing a second primary neoplasm of the head and neck. Possible mechanisms may include immunosuppression inherent in treatment modalities, the disease course of mycosis fungoides, or related genetic mutations.

Clinicopathological spectrum of mycosis fungoides

Journal of the European Academy of Dermatology and Venereology, 2004

Cutaneous lymphomas represent a heterogeneous group of T-, NK-and B-cell neoplasms, with mycosis fungoides (MF) being the most common subtype. MF has a plethora of clinicopathological manifestations. Many variants of this lymphoma differ substantially from the 'classical' Alibert-Bazin disease and are therefore sometimes referred to as 'atypical' forms of the disease. This review addresses the whole clinicopathological spectrum of mycosis fungoides with respect to epidemiology, clinical, histopathological, immunophenotypic and genotypic features and the clinical course and prognosis of its variants: classical, erythrodermic, follicular, syringotropic, bullous/vesicular, granulomatous, poikilodermic, hypo-and hyperpigmented, unilesional, palmoplantar, hyperkeratotic/verrucous, vegetating/papillomatous, ichthyosiform, pigmented purpuralike, pustular and mucosal involvement in MF.

Mycosis Fungoides: Analysis of Ophthalmologic Findings in a Series of Cases

Case Reports in Dermatological Medicine

Background. Ophthalmic findings in mycosis fungoides (MF) can be highly variable. It seems that the prevalence of ophthalmic findings could be much more common than previously assumed. Objective. To present case series examined in the last 12 months, together with a literature review. Methods. Symptomatic patients with biopsy-proven mycosis fungoides were examined ophthalmologically in a 12-month period. The medical records of affected patients were reviewed. Results. Eight patients were examined. Of these, 75% were male, all were Caucasian, and average age was 58.2 years. Blepharitis (50.0%), thickened eyelids (37.5%), and flaking (25.0%) were the most prevalent findings. Conclusion. Incidence of MF affecting the eyes and surrounding structures may be greater than estimated. Early case management offers means to reduce difficulties experienced with later diagnosis. Regular monitoring by an ophthalmologist is justified, including that of asymptomatic cases.

Mycosis fungoides: Review and updates

International journal of dermatology, venereology and leprosy sciences, 2023

Mycosis fungoides is the most common type of cutaneous T cell lymphoma. The early diagnosis of MF is still an area of debate and challenging issue due to its resemblance to chronic inflammatory dermatoses. Therefore, MF diagnosis is usually based on clinical-pathological correlation. Different lines of treatment are available for MF according to the disease staging.