Nuclear Polyhedrosis Virus: A Possible Example of De Novo Intranuclear Membrane Morphogenesis (original) (raw)

The paper explores the role of membranes in the life-cycle of nuclear polyhedrosis viruses (NPV) and granulosis viruses (GV), focusing on the origin and function of various membrane types, particularly envelopes and 'transport' membranes. Observations indicate that NPV infections in the fly Rhynchosciara angelae are restricted to gut epithelial cells without producing 'transport' membranes, leading to the hypothesis that the inner nuclear membrane may serve as a source for virus envelope acquisition. This study highlights the unique aspects of NPV-related intranuclear membrane morphogenesis and its implications for understanding virus-host interactions.