Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126 (original ) (raw )Activation of tumor cell integrin α v β 3 controls angiogenesis and metastatic growth in the brain
Brunie Felding
Proceedings of the National Academy of Sciences, 2009
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Stage-specific expression of integrin alphaVbeta3 in neuroblastic tumors
Ona Faye-Petersen
The American journal of pathology, 1996
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Expression of Integrin α6β1 Enhances Tumorigenesis in Glioma Cells
JOSE LUIS ALONSO
The American Journal of Pathology, 2009
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Expression of Integrin αvβ3in Gliomas Correlates with Tumor Grade and Is not Restricted to Tumor Vasculature
Stefan Grau
Brain Pathology, 2008
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B4GALNT3 Expression Predicts a Favorable Prognosis and Suppresses Cell Migration and Invasion via β1 Integrin Signaling in Neuroblastoma
Min-Chuan Huang , Mei-ieng Che , Wen-ming Hsu
The American Journal of Pathology, 2011
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An α5β1 integrin inhibitor attenuates glioma growth
Nico Van Rooijen
Molecular and Cellular Neuroscience, 2008
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EGFR, PIK3CA and PTEN gene status and their protein product expression in neuroblastic tumours
Wiesława Grajkowska
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences, 2010
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Α2Β1 Integrin Expression in the Tumor Microenvironment Enhances Tumor Angiogenesis in a Tumor Cell–Specific Manner
Norma Xiomahara Tejeda Ramirez
Blood, 2007
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2 1 Integrin Expression in the Tumor Microenvironment Enhances Tumor Angiogenesis in a Tumor Cell-Specific Manner
Laura Ford
Blood, 2008
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Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma
Maria Sciuto
Cell stem cell, 2017
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Integrin-αVβ3 is a fundamental factor in medulloblastoma tumorigenicity and radioresistance: A new game for an old player
régis Amblard
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Malignant Progression and Blockade of Angiogenesis in a Murine Transgenic Model of Neuroblastoma
G. Bergers , Rolf Brekken , Ronit Satchi-fainaro
Cancer Research, 2007
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Integrin Alpha 6 Regulates Glioblastoma Stem Cells
Anita Hjelmeland
Cell Stem Cell, 2010
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Anti-Angiogenic Therapy Induces Integrin-Linked Kinase 1 Up-Regulation in a Mouse Model of Glioblastoma
Giulio Bertani , Chiara Verpelli
PLoS ONE, 2010
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Data from Malignant Progression and Blockade of Angiogenesis in a Murine Transgenic Model of Neuroblastoma
Ronit Satchi-fainaro
2023
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Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities
Maria Pazyra-murphy
Nature Medicine, 2013
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Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy
Aleksandra Ellert-Miklaszewska
International Journal of Molecular Sciences, 2020
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Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression
Fabio Quaglia
PLOS ONE, 2021
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Combination therapy targeting integrins reduces glioblastoma tumor growth through antiangiogenic and direct antitumor activity and leads to activation of the pro-proliferative prolactin pathway
Eva Penas
Molecular Cancer, 2013
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Integrin-αvβ3 is a therapeutically targetable fundamental factor in medulloblastoma tumorigenicity and radioresistance
Thays Blanchard
Cancer research communications, 2023
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Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival
Elisabet Englund
Cancers
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Integrin control of the transforming growth factor- pathway in glioblastoma
Holger Moch
Brain, 2013
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Netrin-1 acts as a survival factor for aggressive neuroblastoma
Valérie Combaret
Journal of Experimental Medicine, 2009
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Faculty of 1000 evaluation for Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma
David Teachey
F1000 - Post-publication peer review of the biomedical literature, 2012
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The αvβ6 integrin in cancer cell‐derived small extracellular vesicles enhances angiogenesis
Fabio Quaglia
Journal of Extracellular Vesicles
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Inhibiting Integrin β8 to Differentiate and Radiosensitize Glioblastoma-Initiating Cells
Vincent Lubrano
Molecular Cancer Research, 2019
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High-level expression of angiogenic factors is associated with advanced tumor stage in human neuroblastomas
Garrett Brodeur
Clinical cancer research : an official journal of the American Association for Cancer Research, 2000
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CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion
Xiuwei Yang
Oncotarget, 2015
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Netrin-1 in Glioblastoma Neovascularization: The New Partner in Crime?
Ximena Espinosa Vásquez
International Journal of Molecular Sciences, 2021
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Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
Mauricio Rosenfeld
Cell, 1994
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