Are There Any Differences in the Neural and Extracellular Matrix Proteins Density Between Children and Adults with Intrinsic Ureteropelvic Junction Obstruction (original) (raw)

Öz What’s known on the subject? and What does the study add? There are lots of studies on the histology of the obstructed segment of UPO patients. Although there are some conflicting results, most of the studies performed to date state that while muscle and neural tissue decrease in UPO, connective tissue and extracellular matrix proteins increase. All these studies have been conducted whether on children or adults. This is the first study that compared the specimens from adult and child population. Our study will help us better understand the progression of ureteropelvic junction obstruction throughout life and create a better understanding on the timing and need of surgery. Are There Any Differences in the Neural and Extracellular Matrix Proteins Density Between Children and Adults with Intrinsic Ureteropelvic Junction Obstruction? Doi: 10.4274/jus.1655 Journal of Urological Surgery, 2017;4(4):177-182