Comparative Study Chromatographic Fractions Activities from Terminalia Ivorensis and Ketoconazole as Standard Antifungal on in Vitro Growth of Trichophyton Mentagrophytes Var. Interdigitale (original) (raw)
The present study was undertaken to evaluate in-vitro antifungal activity of Ketoconazole and extracts from trunk’s barks of Terminalia ivorensis A. Chev (Combretaceae). In vitro antifungal activity of all the extracts was done by agar slant. Extracts were incorporated in Sabouraud medium culture and extract has been inserted to this medium according to the Agar slant method and Ketoconazole were used as standards for antifungal assay. Antifungal activity was determined by diminution of mushroom in the assay tubes. For each extract five tests were done. Antifungal activity was more pronounced against Trichophyton mentagrophytes var. interdigitale. The fraction F8 showed best antifungal activity. T. ivorensis barks extracts showed better antifungal activity than a Ketoconazole. Demonstration of antifungal activity of T. ivorensis provided the scientific basis for the use of this plant in the traditional treatment of diseases and may help to discover new chemical classes of antibiotic...
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