Design and Development of Tooth Paste Containing Alcoholic Extract of Psidium Guajava Leaf (original) (raw)

Extraction of bioactive compounds from Psidium guajava and their application in dentistry

AMB Express, 2019

Guava is considered as poor man’s apple rich in phytochemicals with medicinal value and hence it is highly consumed. Gas chromatography–mass spectroscopy (GC–MS) analysis of guava leaf extract revealed the presence of various bioactive compounds with antimicrobial, antioxidant, anticancer, and antitumor properties. Hence, it is used in tooth paste formulations along with other ingredients such asAcacia arabicagum powder, stevia herb powder, sea salt, extra virgin coconut oil, peppermint oil in the present study. Three formulations F1, F2 and F3 have been made by varying the concentration of these ingredients and the prepared formulations were studied for their antimicrobial activity and physico-chemical parameters such as pH, abrasiveness, foaming activity, spreading and cleaning ability. Among these, F3 showed significant antioxidant and antimicrobial properties, minimal cytotoxicity, maximum spreadability and very high cleaning ability. This study surmises that the herbal toothpas...

Formulation Development and Evaluation of Polyherbal Mouthwash Containing Psidium Guajava L

Journal of Biomedical and Pharmaceutical Research

The mouthwashes prepared from the herbal ingredients has shown great potential to overcome the chemical-based preparations. The combination of two or more herbal ingredients to form a polyherbal formulation has become an efficient approach to add value to the basic herbal formulation. In present study, the polyherbal mouthwash has been prepared using the leaves of Psidium guajava (guava), rhizomes of Curcuma longa (turmeric) and flower buds of Syzygium aromaticum (clove). All the three plant materials were collected and separately extracted. Phytochemical screening and quantitative estimation has been performed. The formulation has been prepared by optimization of different concentrations of used active ingredients. All the prepared formulations had undergone evaluation for organoleptic properties, pH and viscosity. The in-vitro antibacterial study has been performed by agar well diffusion method. The bacteria selected for the study were S. aureus, S. mutans and E. coli. The prepare...

Formulation and Evalua- tion of Herbal Toothpaste: Compared With Marketed Preparation INTERNATIONAL JOURNAL OF PHARMACEUTICS & DRUG ANALYSIS

The aimed of current research to formulate herbal toothpaste utilizing plant extract like Neem leaves, Guava leaves, Cinnamon bark other ingredient are Camphor, Honey. The plant extract ingredient posses the anti-bacterial. The herbal toothpaste formulated which can satisfy all the required condition to keep the mouth fresh and prevent tooth decay by bacteria. The formulated herbal toothpaste compared with marketed preparation. Physical examination: Colour-greenish brown, smooth in nature, relative density-10.2, pH-8.2, Extrudabil-ity-90.37, spredability-Good and stable formulation. The anti-microbial evaluation against Staphylococcus aureus reveal that formulated herbal tooth paste exhibited notable activity with ZOI of 19.7 mm at MIC of 25μg/mL. the outcome of this research herbal toothpaste shows equal patronizing and engrossing passion over the marketed preparation it was consider after the comparing the marketed preparation(Colgate, Dabour Red, Dant-kanti) with formulated herbal toothpaste. It has been good scope in future dental research and det-al health of public.

Formulation and Evaluation of Herbal Oral Emulgel Containing Psidium Guajava Linn. Leaves Extract (A Preventive Oral Care Preparation)

Asian Journal of Pharmaceutical and Clinical Research

Objective: The present research work is based to establish the formulation and evaluation of herbal oral emulgel containing extracts of powdered Psidium guajava Linn. leaves extract. Methods: The guava leaves were collected and extracted by cold maceration process using different solvents, further ethanolic extract was used for the emulgel preparation. Emulsion and gel phase were prepared separately and mixed together in ratio of 1:1. Results: Different formulations ere developed and evaluated for the physical appearance, pH, homogeneity, spreadability, viscosity, extrudability, antibacterial activity, and in vitro skin permeability studies. In all formulated emulgel containing P. guajava Linn. Leaves, extract F2 formulation gives all satisfactory results as in discuss in this paper. Conclusion: Overall, concluded that the extract might contain anti-bacterial properties and further tests are required to prove for oral care activity using other in vivo or in vitro techniques.

Formulation and Evaluation of Herbal Toothpaste: Compared with marketed preparation Formulation and Evaluation of Herbal Toothpaste: Compared with marketed preparation

The aimed of current research to formulate herbal toothpaste utilizing plant extract like Neem leaves, Guava leaves, Cinnamon bark other ingredient are Camphor, Honey. The plant extract ingredient posses the anti-bacterial. The herbal toothpaste formulated which can satisfy all the required condition to keep the mouth fresh and prevent tooth decay by bacteria. The formulated herbal toothpaste compared with marketed preparation. Physical examination: Colour-greenish brown, smooth in nature, relative density-10.2, pH-8.2, Extrudability-90.37, spredability-Good and stable formulation. The anti-microbial evaluation against Staphylococcus aureus reveal that formulated herbal tooth paste exhibited notable activity with ZOI of 19.7 mm at MIC of 25μg/mL. the outcome of this research herbal toothpaste shows equal patronizing and engrossing passion over the marketed preparation it was consider after the comparing the marketed preparation(Colgate, Dabour Red, Dantkanti) with formulated herbal toothpaste. It has been good scope in future dental research and detal health of public.

Formulation and Evaluation of Herbal Toothpaste: Compared With Marketed Preparation

INTERNATIONAL JOURNAL OF PHARMACEUTICS & DRUG ANALYSIS, 2017

The aimed of current research to formulate herbal toothpaste utilizing plant extract like Neem leaves, Guava leaves, Cinnamon bark other ingredient are Camphor, Honey. The plant extract ingredient posses the anti-bacterial. The herbal toothpaste formulated which can satisfy all the required condition to keep the mouth fresh and prevent tooth decay by bacteria. The formulated herbal toothpaste compared with marketed preparation. Physical examination: Colour-greenish brown, smooth in nature, relative density-10.2, pH-8.2, Extrudabil-ity-90.37, spredability-Good and stable formulation. The anti-microbial evaluation against Staphylococcus aureus reveal that formulated herbal tooth paste exhibited notable activity with ZOI of 19.7 mm at MIC of 25μg/mL. the outcome of this research herbal toothpaste shows equal patronizing and engrossing passion over the marketed preparation it was consider after the comparing the marketed preparation(Colgate, Dabour Red, Dant-kanti) with formulated herbal toothpaste. It has been good scope in future dental research and det-al health of public.

Formulation and Evaluation of New Herbal Toothpaste

International Journal of Innovative Research in Technology, 2021

Toothpastes or dentrifrices these are the products which issued for the cleaning, oral hugging or such as freshets of mouth and to avoid tooth decay. The many more dentrifrices prepared by herbal and synthetic tooth paste was prepared by using various herbal products. Which passes or permits antibacterial antiseptic and cooling features. Herbal toothpaste removes it dirt remove bad smell, plantbased toothpaste can also reduce the gingivitis. (Gums become swallow and bleed easily.) it may cause tooth decay. Herbal toothpaste utilizing plantbased extracts like Neemleaves, Guava leaves babool, Cinnamon Bark and other additives honey and Camphor. The formulated herbal toothpaste compared with marketed products physical examination. Colour-greenish brown, smooth in nature the density is 10.0, and ph 8.2, Spreadability-Good and stable formulation. There are some marketed herbal toot past ex. Himalaya, Dabar redtoothpaste Colgate, herbal Toothpaste, Vicco. I.

Formulation Development and Evaluation of Herbal Toothpaste for Treatment of Oral Disease

Journal of Drug Delivery and Therapeutics, 2019

Streptococcus mutans is the most common cause of tooth decay. Parabens and other commonly used as anti-Streptococcus agents in toothpaste industry have numerous side effects such as discoloration of teeth. The herbal extract of all three plants gives antimicrobial and anti-inflammatory activity and prevent and reducing the tooth decay, dental caries and given to freshness of mouth. The aim of present work was development and evaluation of herbal antimicrobial toothpaste containing Bark of Acacia nilotica, Acacia catechu and flower buds of syzygium aromaticum as herbal ingredients. Different types of formulations (F1-F6) were formulated using calcium carbonate as abrasive and Glycerine as humectant in varied concentrations. All the formulations were evaluated for various parameters like dryness, color, appearance, consistency, washability, pH, spreadability and foaming power. Polyherbal toothpaste containing hydroalcoholic extract of plants was tested for antimicrobial activity again...

Formulation and Evaluation of Herbal Toothpaste

International Journal for Research in Applied Science & Engineering Technology (IJRASET), 2022

Neem, "the bitter gem" is one of the most valued trees with many medicinal applications. The scientific name of neem is Azadirachta indica and belongs to Meliaceae family. It is the world's most studied tree in the world and most promising one in the 21st century. Every part of the tree has medicinal value, such as flowers, leaves, neem cake, fruits and seed oil. Almost 300 different phytochemicals have been found in neem tree with versatile application. The aqueous and alcoholic leaf extract of neem is accounted for to have different pharmacological activities. In current situations oral dental care with use of herbal toothpaste containing natural ingredients are more acceptable in public belief than chemical based synthetic formulations due to their safety and efficacy in reducing dental caries, and preventing other dental issues to which this generation is prone to. In this formulation we utilizes clove oil, neem extract, peppermint oil, which are used in this research work. These extracts possess many activities like anti-ulcer, anti-caries, anti-bacterial, wound healing along with which it certain special additional properties like anti-fungal and anti-microbial. Important physical parameters i.e. pH, stability, spreadability, foamability, to make a successful more efficacious and stable formulation. This study that our herbal based toothpaste formulation having natural ingredients.

Preparation and charecterization of Toothpaste of poly herbal plants to treat various tooth problems

Journal of emerging technologies and innovative research, 2021

Every human wants to a healthy teeth so they are use various types of toothpaste to keep their tooth healthy. These toothpastes are minimised the problem of tooth and gum. Generally the toothpaste having many properties to treat such as cavities, bleeding gum and avoid bad smell on mouth. Herbal plants extract are use to formulate good quality of toothpaste. The herbal formulation was prepared by guava leaf, Clove fruit, Neem, honey and several other substances.