Recognising the Sertoli-cell-only (SCO) syndrome: a case study (original) (raw)

AI-generated Abstract

The Sertoli-cell-only (SCO) syndrome is characterized by the absence of germ cells in the testis, affecting male fertility. This case study aims to clarify the distinction between true SCO syndrome and focal SCO, highlighting the importance of accurate diagnosis for effective treatment, particularly testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI). Findings indicate that even in cases of total SCO syndrome, Sertoli cells may be fully matured and capable of supporting spermatogenesis, challenging existing hypotheses surrounding germ cell-Sertoli cell interactions.

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