original ) (raw )Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: Possible implications in controlling dystrophic mineralization in the intervertebral disc
Theresa Freeman
Arthritis & Rheumatism, 2010
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Normoxic stabilization of HIF-1 drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk
Todd Albert
AJP: Cell Physiology, 2007
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Phenotypic characteristics of the nucleus pulposus: expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2
Paul Ducheyne
Cell and Tissue Research, 2002
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Increased HIF-2α Activity in the Nucleus Pulposus Causes Intervertebral Disc Degeneration in the Aging Mouse Spine
Maria Tsingas
bioRxiv (Cold Spring Harbor Laboratory), 2023
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Hypoxia-inducible Factor (HIF)-1α and CCN2 Form a Regulatory Circuit in Hypoxic Nucleus Pulposus Cells
Cassie Tran
Journal of Biological Chemistry, 2013
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Hypoxia-inducible Factor (HIF)-1 and CCN2 Form a Regulatory Circuit in Hypoxic Nucleus Pulposus Cells: CCN2 SUPPRESSES HIF-1 LEVEL AND TRANSCRIPTIONAL ACTIVITY
Karen Lyons
Journal of Biological Chemistry, 2013
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MEK/ERK Signaling Controls Osmoregulation of Nucleus Pulposus Cells of the Intervertebral Disc by Transactivation of TonEBP/OREBP
Todd Albert
Journal of Bone and Mineral Research, 2007
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Differential response of nucleus pulposus intervertebral disc cells to high salt, sorbitol, and urea
E. Mavrogonatou
Journal of Cellular Physiology, 2012
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Expression of Acid-Sensing Ion Channel 3 (ASIC3) in Nucleus Pulposus Cells of the Intervertebral Disc Is Regulated by p75NTR and ERK Signaling
Yoshiyasu Uchiyama
Journal of Bone and Mineral Research, 2007
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Identification of cell surface-specific markers to target human nucleus pulposus cells: Expression of carbonic anhydrase XII varies with age and degeneration
Sibylle Grad , G. Wall , Abhay Pandit , Abhay Pandit
Arthritis & Rheumatism, 2011
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Oxidative stress inhibits the proliferation, induces premature senescence and promotes a catabolic phenotype in human nucleus pulposus intervertebral disc cells
E. Mavrogonatou
European Cells and Materials, 2015
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Differential phenotypic behaviors of human degenerative nucleus pulposus cells under normoxic and hypoxic conditions: influence of oxygen concentration during isolation, expansion, and cultivation
Feng-huei Lin
The spine journal : official journal of the North American Spine Society, 2013
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Role of the Progressive Ankylosis Gene ( ank ) in Cartilage Mineralization
Jinping Xu
Molecular and Cellular Biology, 2004
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Effects of Oxygen Concentration and Culture Time on Porcine Nucleus Pulposus Cell Metabolism: An in vitro Study
Alicia Jackson
Frontiers in Bioengineering and Biotechnology, 2019
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The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP
Flóra Szeri
PLOS Genetics, 2020
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Hypoxia and Hypoxia-Inducible Factor-1α Regulate Endoplasmic Reticulum Stress in Nucleus Pulposus Cells
Emanuel Novais
American Journal of Pathology, 2021
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Part 1: profiling extra cellular matrix core proteome of human fetal nucleus pulposus in search for regenerative targets
Monica Steffi
Scientific Reports, 2020
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Concerted Regulation of Inorganic Pyrophosphate and Osteopontin by Akp2, Enpp1, and Ank
Lovisa Hessle
The American Journal of Pathology, 2004
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Oxygen tension regulates the expression of ANK (progressive ankylosis) in an HIF-1-dependent manner in growth plate chondrocytes
Theresa Freeman
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2009
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Gene Expression of Notochordal Nucleus Pulposus Cells Following Prolonged Culture at Varied Nutrient Levels
Alicia Jackson
2015
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Reflections on the Nucleus Pulposus
luigi simonetti
Rivista di Neuroradiologia, 1998
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Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration
Kanna Gnanalingham
Scientific reports, 2017
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Expression and effects of leukemia inhibitory factor on nucleus pulposus degeneration
Jeffrey Roh
Molecular Medicine Reports
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TonEBP/OREBP Is a Regulator of Nucleus Pulposus Cell Function and Survival in the Intervertebral Disc
Tsung-Ting Tsai
Journal of Biological Chemistry, 2006
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High osmolality activates the G1 and G2 cell cycle checkpoints and affects the DNA integrity of nucleus pulposus intervertebral disc cells triggering an enhanced DNA repair response
E. Mavrogonatou
DNA Repair, 2009
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Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration
Sibylle Grad
Osteoarthritis and Cartilage, 2010
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Hyperbaric oxygen treatment suppresses MAPK signaling and mitochondrial apoptotic pathway in degenerated human intervertebral disc cells
Po-Liang Lai , Song-shu Lin
Journal of Orthopaedic Research, 2013
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Mineral Formation in Joints Caused by Complete or Joint-Specific Loss of ANK Function
Ryan Rountree
Journal of Bone and Mineral Research, 2006
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Profiling extra cellular matrix associated proteome of human fetal nucleus pulposus in search for regenerative targets
Chitra Thangavel
Scientific Reports, 2021
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