Influence of a Melatonin Implant on the Free Radical Load In Avian Thydroid and Its Relation With Thyroid Hormonogenesis (original) (raw)

This study investigates the influence of melatonin implantation on free radical production in the avian thyroid and its relationship with thyroid hormone synthesis. Key findings indicate that 2-week melatonin implantation leads to significant oxidative stress in avian thyroid glands, characterized by increased lipid peroxidation and superoxide levels, which subsequently inhibit the release of thyroid hormones including thyroxine (T4) and triiodothyronine (T3). The results suggest that melatonin-induced elevated glucose levels may contribute to oxidative injury within the thyroid.